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 +===== COVID-19 Case Reports Abstracts - Page 8 =====
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 +[[oa_db:​covid19_case_reports_abstracts|Back to Table of Contents]]
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 +----------------------------------------------------------------------<​br>​
 +<​b>​[417] Title: </​b>​Prolonged Confusional state as first manifestation of COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.75<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-20<​br>​
 +<​b>​Publisher:​ </​b>​Annals of Clinical and Translational Neurology<​br>​
 +<​b>​Keywords:​ </b>, covid-19, delirium, neuropathology,​ sars-cov-2<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​acn3.51067">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​acn3.51067</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +A 77 year old gentleman, normally fit and well, was admitted with acute confusion. On admission GCS was 14/15, vital signs were within the normal limits and bilateral crepitation at the lung base. Head CT scan normal. CXR showed some air space opacification. Investigations revealed hyponatraemia,​ raised CRP and positive for COVID-19. Treated with antibiotics and intravenous saline, sodium returned to normal. Delirium remained unchanged four weeks post incidence. Neurological manifestations were documented in patients with COVID-19, however no report has shown delirium as a primary manifestation. This case illustrates acute confusion may be the only presenting symptom of COVID-19 without overt lung disease.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[418] Title: </b>A Case of COVID-19 Patient with False-negative for SARS-CoV-2 of Pharyngeal Swab, from a Chinese traveller Returning from Wuhan, Hubei Province, China, January 2020.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.75<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-01-01<​br>​
 +<​b>​Publisher:​ </​b>​Japanese Journal of Infectious Diseases<​br>​
 +<​b>​Keywords:​ </b>, covid-19, false-negative of pharyngeal swab, sars-cov-2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.jstage.jst.go.jp/​article/​yoken/​advpub/​0/​advpub_JJID.2020.240/​_article">​https://​www.jstage.jst.go.jp/​article/​yoken/​advpub/​0/​advpub_JJID.2020.240/​_article</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We report a case of patient in Japan with Coronavirus disease 2019 (COVID-19) with false-negative of reverse transcription polymerase chain reaction for Severe Acute Respiratory Syndrome Coronavirus 2 of pharyngeal swab, from a Chinese traveller returning from Wuhan, Hubei Province, China. If a patient is clinically or epidemiologically suspected of COVID-19, appropriate infection and prevention control measures such as standard, contact, and droplet precaution are needed until the patient is proven to be true-negative.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[419] Title: </​b>​COVID-19 Presented With Deep Vein Thrombosis: An Unusual Presenting.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.75<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-04<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Investigative Medicine High Impact Case Reports<​br>​
 +<​b>​Keywords:​ </b>, covid-19, bilateral patchy ground-glass opacity, deep vein thrombosis, pulmonary thromboembolism<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.sagepub.com/​doi/​10.1177/​2324709620931239">​https://​journals.sagepub.com/​doi/​10.1177/​2324709620931239</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +On December 31, 2019, the World Health Organization was informed of a cluster of cases of pneumonia of unknown cause detected in Wuhan City, Hubei Province, China. The pneumonia was caused by a virus called SARS-Cov-2 (severe acute respiratory syndrome coronavirus 2), which was later named coronavirus infectious disease 2019 (COVID-19). The symptoms most commonly reported by patients affected by COVID-19 include fever, dry cough, and shortness of breath. In this report, we present a case of a 57-year-old woman who presented to the clinic'​s infectious department with swelling, pain, warmth, and redness in the left leg who was treated with therapeutic heparin. There were no typical and distinguished symptoms of COVID-19, and she had no risk factor for deep vein thrombosis. Then chest X-ray revealed bilateral patchy ground-glass opacity, and computed tomography angiography was performed to rule out pulmonary thromboembolism,​ which showed no evidence of thrombosis. Left lower limb venous color Doppler ultrasound revealed dilatation and thrombosis in the external iliac and left iliac veins up to the level of the bifurcation of the common iliac veins, as well as thrombosis to the superficial and small saphenous veins. Because of ground-glass opacity and lymphopenia,​ nasal swabs were used for sampling, and SARS-CoV-2 nucleic acid was detected by reverse transcription polymerase chain reaction (RT-PCR). This case aims to arouse the medical staff'​s awareness of deep vein thrombosis as a clinical symptom of COVID-19 even if the patient has no typical symptoms of COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[420] Title: </​b>​The Coincidence of 2 Epidemics, Coccidioidomycosis and SARS-CoV-2: A Case Report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.75<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-04<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Investigative Medicine High Impact Case Reports<​br>​
 +<​b>​Keywords:​ </b>, covid19, cov-2, sars-cov-2, cavitary coccidioidomycosis,​ corona virus, pneumonia, pulmonary coccidioidomycosis<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.sagepub.com/​doi/​10.1177/​2324709620930540">​https://​journals.sagepub.com/​doi/​10.1177/​2324709620930540</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +In the middle of a pandemic, patients with cough and fever are thought to have SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). It should be remembered that in the desert southwest of the United States, we have an ongoing epidemic of coccidioidomycosis (CM). There are additionally many other respiratory illnesses that could be confused with CoV-2 or overlooked. This is a case report of CoV-2 engrafted on chronic cavitary pulmonary CM. In a time where the coronavirus pandemic is becoming rampant, we demonstrate the case of a coinfection with cavitary pulmonary CM. In this case, the importance of detection of the coronavirus and treatment of the coinfection is explored.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[421] Title: </​b>​Oral mucosal lesions in a COVID-19 patient: new signs or secondary manifestations?<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.75<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​International Journal of Infectious Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Microbiology,​ covid-19, candidiasis,​ case report, geographic tongue, oral conditions, recurrent herpes simplex, sars-cov-2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1201971220304471">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1201971220304471</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Some oral manifestations have been observed in patients with coronavirus disease in 2019 (COVID-19). However, there is still a question about whether these lesions are due to coronavirus infection or secondary manifestations resulting from the patient'​s systemic condition. Thus, this article aims to report an additional case of the oral conditions in a patient diagnosed with COVID-19. Our patient, a sixty-seven-year-old Caucasian man, tested positive to coronavirus and presented oral manifestations such as recurrent herpes simplex, candidiasis,​ and geographic tongue. We support the argument that some oral conditions could be secondary to the deterioration of systemic health or due to treatments for COVID-19. The present case report highlights the importance of including dentists in the intensive care unit multi-professional team to improve oral health in critical patients not only COVID-19 patients. Also, to contribute to evidence-based and decision-making in managing infectious diseases.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[422] Title: </​b>​ITP flare with mild COVID-19 infection in pregnancy: A case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.6<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-09<​br>​
 +<​b>​Publisher:​ </​b>​British Journal of Haematology<​br>​
 +<​b>​Keywords:​ </​b>​Cardiovascular Medicine And Haematology,​ , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​bjh.16928">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​bjh.16928</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the third zoonotic coronavirus to be identified in humans during the twenty-first century, after severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV)(Coronaviridae Study Group of the International Committee on Taxonomy,of Viruses, 2020). The resultant disease, Coronavirus Disease (COVID-19) (WHO, 2020), was first identified in December 2019 in Wuhan, Hubei province, China (WHO, 2020) and rapidly evolved into a pandemic (WHO, 2020) within months. In the UK, the first confirmed case was identified in late January 2020 and the first COVID-19 related death was recorded in March 2020 (UK Government, 2020).<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[423] Title: </b>A Case Report of Rapidly Lethal Acute Respiratory Distress Syndrome Secondary to Coronavirus Disease 2019 Viral Pneumonia.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.6<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-21<​br>​
 +<​b>​Publisher:​ </​b>​Cureus<​br>​
 +<​b>​Keywords:​ </b>, acute respiratory distress syndrome, berlin criteria, coronavirus disease (covid-19)<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.cureus.com/​articles/​32512-a-case-report-of-rapidly-lethal-acute-respiratory-distress-syndrome-secondary-to-coronavirus-disease-2019-viral-pneumonia">​https://​www.cureus.com/​articles/​32512-a-case-report-of-rapidly-lethal-acute-respiratory-distress-syndrome-secondary-to-coronavirus-disease-2019-viral-pneumonia</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +As of April 2020, the coronavirus 2019 (COVID-19) pandemic has resulted in more than 210,000 deaths globally. The most common cause of death from COVID-19 is acute respiratory failure. We report the case of a 78-year-old female with a history of hypertension,​ cerebrovascular accident (CVA), type 2 diabetes mellitus, and sarcoidosis,​ who presented to the emergency department with one day of dyspnea. The patient experienced a rapid decline in respiratory function and was intubated in the intensive care unit (ICU), meeting the Berlin criteria for severe acute respiratory distress syndrome (ARDS). Chest radiography revealed diffuse bilateral coalescent opacities, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA swab test was positive for COVID-19. The patient experienced acute kidney injury with uptrending creatinine levels and remained lethargic and unresponsive throughout her ICU stay, suggestive of potential hypoxic brain injury. In light of the patient'​s poor clinical status, age, and significant comorbidities,​ prognosis was conveyed about medical futility and patient'​s family agreed to terminal extubation and the patient expired peacefully, exactly one week from hospital admission. This case report highlights the speed at which severe ARDS can present and contribute to end-organ dysfunction in COVID-19 patients.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[424] Title: </​b>​SARS-CoV-2 infection in a patient on chronic hydroxychloroquine therapy: Implications for prophylaxis.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-01-01<​br>​
 +<​b>​Publisher:​ </​b>​IDCases<​br>​
 +<​b>​Keywords:​ </b>, covid19, hydroxychloroquine,​ pandemic, sars-cov-2<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S221425092030086X">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S221425092030086X</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +People exposed to COVID-19 have a risk of developing disease, and health care workers are at risk at a time when they are badly needed during a health care crisis. Hydroxychloroquine and chloroquine have been used as treatment and are being considered as prophylaxis. Our patient developed COVID-19 while on hydroxychloroquine and although more work is needed, this calls into question the role of these medications as preventive therapy.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[425] Title: </​b>​Acute Inflammation and Elevated Cardiac Markers in a Two-Month-Old Infant with Severe Acute Respiratory Syndrome Coronavirus 2 Infection Presenting with Cardiac Symptoms.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-19<​br>​
 +<​b>​Publisher:​ </​b>​The Pediatric Infectious Disease Journal<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​pidj/​FullText/​2020/​07000/​Acute_Inflammation_and_Elevated_Cardiac_Markers_in.35.aspx">​https://​journals.lww.com/​pidj/​FullText/​2020/​07000/​Acute_Inflammation_and_Elevated_Cardiac_Markers_in.35.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Severe acute respiratory syndrome coronavirus 2 infection in children mainly shows a milder course. In complicated cases, it is unknown whether inflammation is predictive of disease severity, as in adults. Moreover, cardiac involvement is anecdotally described. We report the case of a 2-month-old infant with severe acute respiratory syndrome coronavirus 2 infection presenting with fever, tachycardia and elevated interleukin-6,​ who was diagnosed with myocarditis and treated with immunoglobulins.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[426] Title: </​b>​Therapeutic effect of high-flow nasal cannula on severe COVID-19 patients in a makeshift intensive-care unit: A case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-22<​br>​
 +<​b>​Publisher:​ </​b>​Medicine<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​md-journal/​FullText/​2020/​05220/​Therapeutic_effect_of_high_flow_nasal_cannula_on.95.aspx">​https://​journals.lww.com/​md-journal/​FullText/​2020/​05220/​Therapeutic_effect_of_high_flow_nasal_cannula_on.95.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +INTRODUCTION:​ Several intensive-care units (ICUs) in Wuhan are nonstandard wards that were repurposed from general wards. Considering the shortage of medical resources and the need to prevent nosocomic infection, the respiratory-treatment strategy in these nonstandard ICUs is different from those in general wards and standard ICUs. High-flow nasal cannula (HFNC) plays an important role in nonstandard ICUs and is beneficial to the patients therein. PATIENT CONCERNS: In this study, we analyzed four cases of HFNC-treated patients with severe coronavirus disease 2019 (COVID-19) in a makeshift ICU and summarized our experience. DIAGNOSES: Four patients diagnosed with COVID-19 according to World Health Organization (WHO) interim guidance were admitted to the makeshift ICU. INTERVENTIONS:​ All patients had oxygen treatment with HFNC, as well as regular treatment of antivirals and traditional Chinese medicine. OUTCOMES: Two patients survived after treatment, while the other two died from acute respiratory distress syndrome (ARDS) and heart failure, respectively. CONCLUSION: Patients with severe and critical COVID-19 often have poor prognoses after mechanical ventilation,​ exhibiting corresponding complications such as ventilator-associated pneumonia and deep-vein thrombosis, which significantly prolongs length of stay in the ICU. HFNC could prevent intubation in some patients, thereby avoiding the above complications;​ however, this needs confirmation in further clinical studies. This treatment reduced difficulty and workloads for healthcare professionals,​ had good tolerability for patients, might not significantly increase the risk of infection for healthcare professionals,​ and do not require additional preventive measures against nosocomic infection. HFNC treatment has its advantages in providing oxygen therapy in COVID-19, but healthcare professionals should still pay close attention to changes in patients'​ oxygenation rates and respiratory frequency.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[427] Title: </​b>​Can COVID 19 present like appendicitis?<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-01-01<​br>​
 +<​b>​Publisher:​ </​b>​IDCases<​br>​
 +<​b>​Keywords:​ </b>, ace2, ace2, angiotensin-converting enzyme 2, ards, acute respiratory distress syndrome, appendicitis,​ cdc, communicable diseases center, covid-19, covid-19, coronavirus disease-19, mcv, mean corpuscular volume, pandemic, pneumonia, sars, severe acute respiratory syndrome, who, world health organization<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2214250920301682">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2214250920301682</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease -19 is a novel pandemic contagious respiratory infection that frequently presents with fever and dry cough. However, it can present with other rare symptoms. As this disease is a new disease, the full picture of the disease presentation is not yet clear, and it might present with symptoms and signs of other common diseases. Here, we report a 40 year old female who presented with acute onset nausea, vomiting, loss of appetite and vague abdominal pain as a clinical picture of appendicitis,​ but her CT abdomen image showed normal appendix, bilateral patchy peripheral lung basal consolidation,​ and ground-glass attenuation,​ so she was tested for coronavirus disease-19, which was positive.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[428] Title: </​b>​Rash as a presenting complaint in a child with COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-11<​br>​
 +<​b>​Publisher:​ </​b>​Pediatric Dermatology<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, covid-19, sars-cov-2; coronavirus,​ child, pediatric, rash, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​pde.14257">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​pde.14257</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Cutaneous manifestations are becoming increasingly well-documented in adults with COVID-19. There is now also a growing body of literature regarding skin involvement in children, with reports of papulovesicular,​ petechial and widespread macular and papular lesions, as well as chilblains (pernio). We describe the case of a thirteen-year-old boy with confirmed COVID-19 in the United Kingdom who presented with skin findings localized to the plantar aspects of the feet, axillae and lower limbs. The morphology was predominantly maculopapular but also included petechiae and annular lesions.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[429] Title: </​b>​Flight of the COVID-19 patient: experience with a Wuhan evacuee: a case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-11<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Medical Case Reports<​br>​
 +<​b>​Keywords:​ </​b>​Other Medical And Health Sciences, 2019 novel coronavirus,​ covid-19, quarantine, remdesivir, sars-cov-2, severe acute respiratory syndrome coronavirus 2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​jmedicalcasereports.biomedcentral.com/​articles/​10.1186/​s13256-020-02396-8">​https://​jmedicalcasereports.biomedcentral.com/​articles/​10.1186/​s13256-020-02396-8</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2, was declared a global pandemic by the World Health Organization in March 2020. CASE PRESENTATION:​ We report a case of a 51-year-old Chinese woman who was evacuated from Wuhan, China and diagnosed with coronavirus disease 2019 infection at a Southern California quarantine facility. Her clinical course was notable for high fevers, night sweats, productive cough, transient leukopenia, lymphopenia,​ thrombocytopenia,​ and transaminitis. Evolving hypoxia and infiltrates on chest imaging warranted the trial of an investigational antiviral drug - remdesivir. Our patient recovered and was discharged after 2 weeks of hospitalization. CONCLUSIONS:​ This case highlights our patient'​s clinical course, including diagnostic work-up, medical management, and challenges in defining non-infectivity in a relatively unknown disease.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[430] Title: </​b>​Takotsubo cardiomyopathy triggered by SARS-CoV-2 infection in a critically ill patient.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-14<​br>​
 +<​b>​Publisher:​ </​b>​BMJ Case Reports<​br>​
 +<​b>​Keywords:​ </b>, adult intensive care, cardiovascular medicine, heart failure, infectious diseases<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​casereports.bmj.com/​lookup/​doi/​10.1136/​bcr-2020-236561">​https://​casereports.bmj.com/​lookup/​doi/​10.1136/​bcr-2020-236561</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +COVID-19 became a global pandemic in early 2020. While well known for its pulmonary manifestations,​ the virus also has a number of cardiac manifestations as well. Takotsubo syndrome has scarcely been reported in patients with COVID-19, but it is possible that the cytokine storm associated with the infection can trigger Takotsubo syndrome in patients with underlying risk factors for Takotsubo (emotional distress, physical distress, history of psychiatric disorders).<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[431] Title: </​b>​Withdrawing mycophenolate mofetil in treating a young kidney transplant recipient with COVID-19: A case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-12<​br>​
 +<​b>​Publisher:​ </​b>​Medicine<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​md-journal/​FullText/​2020/​06120/​Withdrawing_mycophenolate_mofetil_in_treating_a.27.aspx">​https://​journals.lww.com/​md-journal/​FullText/​2020/​06120/​Withdrawing_mycophenolate_mofetil_in_treating_a.27.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +RATIONALE: Coronavirus disease 2019 (COVID-19) is a novel infectious disease and became a global issue. Treatment of COVID-19 especially in solid organ transplant recipients is empirical and controversial,​ especially the adjustment of the immunosuppressants. PATIENT CONCERNS: A 29-year-old kidney transplant recipient with the symptoms of COVID-19 pneumonia. DIAGNOSES: COVID-19 pneumonia after kidney transplantation. INTERVENTIONS:​ He was treated with modified immunosuppressants (unchanged dose of tacrolimus and oral corticosteroids while discontinuing mycophenolate mofetil (MMF)), antibiotics,​ interferon alpha-2b inhalation and traditional Chinese medicine. OUTCOMES: He recovered from COVID-19 pneumonia after 29 days of hospitalization. And the renal function (measured as blood urea nitrogen, serum creatinine, and urine protein) returned to normal. LESSONS: In certain group of COVID-19 (e.g., mild to moderate cases, young patients without comorbidities),​ a reduction instead of an overall withdrawal of immunosuppressant in kidney transplant recipients is feasible.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[432] Title: </​b>​Chest CT Findings of Early and Progressive Phase COVID-19 Infection from a US Patient.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.35<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Radiology Case Reports<​br>​
 +<​b>​Keywords:​ </b>, acr, american college of radiology, covid-19, coronavirus disease 2019, covnet, covid-19 detection neural network, ct, computed tomography, dad, diffuse alveolar damage, ggo, ground glass opacity, icu, intensive care unit, pcr, polymerase chain reaction, sars-cov-1 infection, severe acute respiratory syndrome coronavirus from the 2003 outbreak, sars-cov-2 infection, severe acute respiratory syndrome coronavirus 2, sdu, step down unit, rrt-pcr, real-time reverse transcriptase polymerase chain reaction<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1930043320301370">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1930043320301370</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The SARS-CoV-2 infection (COVID-19), originally reported in Wuhan, China, has rapidly proliferated throughout several continents and the first case in the United States was reported on January 19, 2020. According to the ACR guidelines issued shortly after this disease was declared a pandemic, radiologists are expected to familiarize themselves with the CT appearance of COVID-19 infection in order to be able to identify specific findings of this entity. This case report discusses the relevant imaging findings of one of the first cases in the midwestern US. It involves a 60-year-old man who presented with fever, dyspnea, and cough for 1 week and subsequently tested positive for COVID-19. The utility of the noncontrast CT chest in the diagnosis of COVID-19 has been controversial,​ but there are specific imaging findings that have been increasingly associated with this virus in the appropriate clinical context. The stages of imaging findings in COVID-19 are considered along with the implications of fibrosis throughout the stages. Future considerations include using artificial intelligence algorithms to distinguish between community acquired pneumonias and COVID-19 infection.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[433] Title: </​b>​Neurological Complications of Coronavirus Disease (COVID-19): Encephalopathy,​ MRI Brain and Cerebrospinal Fluid Findings: Case 2.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.35<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-02<​br>​
 +<​b>​Publisher:​ </​b>​Cureus<​br>​
 +<​b>​Keywords:​ </b>, covid 19<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.cureus.com/​articles/​31252-neurological-complications-of-coronavirus-disease-covid-19-encephalopathy-mri-brain-and-cerebrospinal-fluid-findings-case-2">​https://​www.cureus.com/​articles/​31252-neurological-complications-of-coronavirus-disease-covid-19-encephalopathy-mri-brain-and-cerebrospinal-fluid-findings-case-2</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The neurological complications of coronavirus disease 2019 (COVID-19) are being better understood as the pandemic progresses. We report a second case of a patient who presented with COVID-19 infection and encephalopathy to our institution. In addition, we report MRI brain and cerebrospinal fluid data. COVID-19 does not seem to cross the blood-brain barrier. The exact mechanisms of encephalopathy and pathological response of COVID-19 are unknown.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[434] Title: </​b>​Ventilation/​perfusion SPECT/CT findings in different lung lesions associated with COVID-19: a case series.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.35<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-18<​br>​
 +<​b>​Publisher:​ </​b>​European Journal of Nuclear Medicine & Molecular Imaging<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-19, coagulopathy,​ pulmonary embolism, v/q spect, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​link.springer.com/​article/​10.1007/​s00259-020-04920-w">​https://​link.springer.com/​article/​10.1007/​s00259-020-04920-w</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +PURPOSE: The aim of this series of cases is to show the aspects of ventilation/​perfusion single-photon emission computed tomography combined with computed tomography (V/Q SPECT/CT) in patients hospitalized for COVID-19 pneumonia, with the worsening of respiratory symptoms raising the suspicion of a pulmonary embolism. Patients did not benefit from CT angiography for various reasons: a contraindication,​ unavailability of the CT angiography,​ or a low clinical probability for pulmonary embolism. METHODS: We retrospectively describe the results of the V/Q SPECT/CT of five patients hospitalized for COVID-19 pneumonia in the nuclear medicine departments of the Centre Cardiologique du Nord and of the Delafontaine hospital in Saint-Denis (Ile-de-France,​ France) between April 2, 2020, and April 10, 2020. These patients had persistent dyspnea or chest pain suggesting pulmonary embolism. RESULTS: The V/Q SPECT/CT allowed to diagnose a pulmonary embolism in one of these five patients. We also noted several characteristics of the perfusion and ventilation depending on the lung lesions on the CT scan. The areas affected by COVID-19 were most often responsible for ventilatory anomalies with a relatively preserved perfusion. In more advanced cases of pneumonia, with alveolar fillings, the perfusion was also reduced or absent in accordance with large ventilation defects. In addition, the healthy parenchyma appeared to benefit from an uptake in ventilation and perfusion. CONCLUSION: V/Q SPECT/CT can play a role in the management of patients hospitalized for COVID-19 for the diagnosis of embolic complications with meticulous hygienic precautions. The different characteristics of the ventilatory and perfusion anomalies related to COVID-19 pneumonia will be confirmed with the next cases. In addition, in this pandemic context and facing a significant infectious risk, the utility of ventilation will also have to be specified.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[435] Title: </​b>​Coronavirus disease 2019: favorable outcome in an immunosuppressed patient with multiple sclerosis.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.35<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-20<​br>​
 +<​b>​Publisher:​ </​b>​Neurological Sciences<​br>​
 +<​b>​Keywords:​ </​b>​Medicine & Public Health, covid-19, immunosuppression,​ multiple sclerosis, rituximab, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​link.springer.com/​article/​10.1007/​s10072-020-04522-2">​https://​link.springer.com/​article/​10.1007/​s10072-020-04522-2</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The rapid and global spread of severe acute respiratory syndrome coronavirus 2, a viral pathogen responsible for the development of the "​coronavirus disease of 2019" (COVID-19), has developed into an unprecedented health crisis with considerable case fatality rate. Patients with comorbidities are considered to be at higher risk for severe disease with acute respiratory failure, intensive care unit admission, and/or death. Particular vigilance has been warranted regarding the continuation of immunosuppressive treatments since viral clearing may be hampered in such cases. In contrast, it has also been hypothesized that overactive immune responses may trigger a cytokine storm associated with clinical deterioration,​ which has generated an interest in certain immunosuppressant drugs as potential treatment for COVID-19. We would like to present the first case report of a patient who was formally diagnosed with COVID-19 while being under disease-modifying treatment with rituximab, an anti-CD20 B cell depleting agent, for multiple sclerosis. The clinical picture was mild for which we have tried to provide an immunopathological framework.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[436] Title: </​b>​Pulmonary infiltration shadows associated with acute aortic dissection mimicking coronavirus pneumonia.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-10<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Cardiac Surgery<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, aortic dissection, pulmonary infiltration,​ subadventitial hematoma, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​jocs.14533">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​jocs.14533</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: In acute aortic dissection, various findings can be found in computed tomography. However, pulmonary infiltration is rarely observed. CASE REPORT: A 57-year-old man was diagnosed with acute aortic dissection (AAD), but had marked infiltration shadows in his right lung. Intraoperative findings showed that large subadventitial hematomas had spread from the ascending aorta to the right pulmonary artery, which may have caused the infiltration of the lung. CONCLUSIONS:​ Subadventitial hematoma must be considered in rare cases of AAD with pulmonary infiltration.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[437] Title: </b>A case of imported COVID-19 diagnosed by PCR-positive lower respiratory specimen but with PCR-negative throat swabs.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-02<​br>​
 +<​b>​Publisher:​ </​b>​Infectious Diseases<​br>​
 +<​b>​Keywords:​ </b>, coronavirus disease 2019 (covid-19), real-time reverse transcription-polymerase chain reaction (rt-pcr) assay, the novel corona virus (sars-cov-2)<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.tandfonline.com/​doi/​full/​10.1080/​23744235.2020.1744711">​https://​www.tandfonline.com/​doi/​full/​10.1080/​23744235.2020.1744711</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +A 35-year-old woman presented with fever and mild diarrhoea without any respiratory symptoms 9 days after travelling to Japan from Wuhan, China. Her computed tomography scan revealed pneumonia. The first polymerase chain reaction (PCR) test on throat swab for the novel corona virus upon admission was negative. Therefore, she was treated for community-acquired pneumonia, but fever persisted. On hospital day 5, PCR test on induced sputum was positive, but a second polymerase chain reaction test on throat swab remained negative. She was discharged, fully recovered, on hospital day 12. A lower respiratory tract specimen should be obtained for better diagnosis of corona virus disease 2019, even in the absence of respiratory symptoms for patients with significant travel or exposure history.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[438] Title: </​b>​Clinical Characteristics of COVID-19 After Gynecologic Oncology Surgery in Three Women: A Retrospective Review of Medical Records.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-07<​br>​
 +<​b>​Publisher:​ </​b>​Oncologist<​br>​
 +<​b>​Keywords:​ </​b>​Oncology And Carcinogenesis,​ , Biochemistry,​ Genetics and Molecular Biology, Health Sciences, Life Sciences, Medicine<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1634/​theoncologist.2020-0157">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1634/​theoncologist.2020-0157</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +From a large medical center in Wuhan, the epicenter of the 2019 novel coronavirus disease (COVID-19), we report clinical features and prognosis for three women diagnosed with COVID-19 after gynecologic oncology surgery and hospitalized in January 2020. The incidence of COVID-19 was 0.77% (3 of 389) of total hospitalizations and 1.59% (3 of 189) of patients undergoing surgeries in the ward. The infection of severe acute respiratory syndrome coronavirus 2 may be related to the older age, comorbidities,​ malignant tumor, and surgery in gynecologic hospitalizations. By February 20, 2020, only two of the three patients had met the clinical discharge criteria. Given the long and uncertain incubation period of COVID-19, screening for the virus infection should be carried out for all patients, both preoperatively and postoperatively. Postponement of scheduled gynecologic surgery for patients in the epidemic area should be considered.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[439] Title: </​b>​Threatening drug-drug interaction in a kidney transplant patient with Coronavirus Disease 2019 (COVID-19).<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-12<​br>​
 +<​b>​Publisher:​ </​b>​Transplant Infectious Disease<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-19, drug-drug interaction,​ kidney transplant, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​resolve/​doi?​DOI=10.1111/​tid.13286">​https://​onlinelibrary.wiley.com/​resolve/​doi?​DOI=10.1111/​tid.13286</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +During the novel coronavirus pandemic, organ transplant recipients represent a frail susceptible category due to long-term immunosuppressive therapy. For this reason, clinical manifestations may differ from general population and different treatment approaches may be needed. We present the case of a 36-year-old kidney transplanted woman affected by Senior-Loken syndrome diagnosed with COVID-19 pneumonia after a contact with her positive mother. Initial symptoms were fatigue, dry cough and coryza; she never had fever nor oxygen supplementation. Hydroxychloroquine and lopinavir/​ritonavir were started, and the antiviral drug was replaced with darunavir/​cobicistat after two days for diarrhea. Immunosuppressant levels were closely monitored, and we observed very high tacrolimus trough levels despite initial dose reduction. The patient was left with steroid therapy alone. The peculiarity of clinical presentation and the management difficulties represent the flagship of our case-report. We stress the need for guidelines in transplant recipients with COVID-19 infection with particular regard to the management of therapy.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[440] Title: </​b>​Clinical features and multidisciplinary treatment outcome of COVID-19 pneumonia: A report of three cases.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-01<​br>​
 +<​b>​Publisher:​ </​b>​Journal of the Formosan Medical Association<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, covid-19, multidisciplinary therapeutic approach, sars-cov-2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0929664620301443">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0929664620301443</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic threatening global public health. In the current paper, we describe our successful treatment of three COVID-19 pneumonia patients cases including severe cases and cases with mortality risk factors. One 32-year-old male COVID-19 patient was diagnosed with severe COVID-19 pneumonia and moderate ARDS. The second COVID-19 pneumonia patient had a history of diabetes and chronic bronchitis. The third case of COVID-19 pneumonia was an 82-year old female patient. All three cases had severe COVID pneumonia and therefore were aggressively managed with a multidisciplinary and personalized therapeutic approach that included nutritional support, antiviral pharmacotherapy,​ active control of comorbidities,​ prevention of complication development and psychological intervention. Our experience highlights the importance of the use of a multidisciplinary therapeutic approach that tailors to the specific condition of the patient in achieving a favorable clinical outcome.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[441] Title: </​b>​The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-22<​br>​
 +<​b>​Publisher:​ </​b>​Respiratory Research<​br>​
 +<​b>​Keywords:​ </​b>​Medicine & Public Health, covid-19, ct image, nucleic acid detection, sars-cov-2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​respiratory-research.biomedcentral.com/​articles/​10.1186/​s12931-020-01363-7">​https://​respiratory-research.biomedcentral.com/​articles/​10.1186/​s12931-020-01363-7</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease progress, whereas the continued two times of negative results from SARS-CoV-2 nucleic acid detection had been considered as a criterion for ending antiviral treatment. We compared the two COVID-19 cases with similar backgrounds and CT image repeated intervals under treatment. Our report highlighted the unsynchronized expression in the changes of CT image and nucleic acid detection in COVID-19, and lasting positive nucleic acid test result in patients recovered from pneumonia. It may be contributed to recognize the disease and improve prevention.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[442] Title: </​b>​Isolation protocol for a COVID-2019 patient requiring emergent surgical intervention:​ case presentation.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-19<​br>​
 +<​b>​Publisher:​ </​b>​Patient Safety in Surgery<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-2019, emergency surgery, infection control, sars-cov-2<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​pssjournal.biomedcentral.com/​articles/​10.1186/​s13037-020-00243-9">​https://​pssjournal.biomedcentral.com/​articles/​10.1186/​s13037-020-00243-9</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Background: The concerns of the highly contagious and morbid nature of Coronavirus Disease-2019 (COVID-2019) have prompted healthcare workers to implement strict droplet and contact isolation precautions. Unfortunately,​ some patients who may be or presumptively or confirmed as infected with COVID-2019 may also require emergent surgical procedures. As such, given the high-risk for exposure of many healthcare workers involved the complex requirements for appropriate isolation must be adhered to. Case presentation:​ We present our experience with a 77-year-old who required emergency cardiac surgery for a presumed acute aortic syndrome in the setting of a presumed, and eventually confirmed, COVID-2019 infection. We outline the necessary steps to maintain strict isolation precautions to limit potential exposure to the surgical Team. Conclusions:​ We hereby provide our algorithm for emergent surgical procedures in critically-ill patients with presumptive or confirmed infection with COVID-2019. The insights from this case report can potentially be templated to other facilities in order to uphold high standards of infection prevention and patient safety in surgery during the current COVID-19 pandemic.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[443] Title: </​b>​Corona Virus Disease 2019 (COVID-19) Presenting as Acute ST Elevation Myocardial Infarction.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-22<​br>​
 +<​b>​Publisher:​ </​b>​Cureus<​br>​
 +<​b>​Keywords:​ </b>, acute respiratory distress syndrome, atypical covid, covid-19, stemi<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.cureus.com/​articles/​30976-corona-virus-disease-2019-covid-19-presenting-as-acute-st-elevation-myocardial-infarction">​https://​www.cureus.com/​articles/​30976-corona-virus-disease-2019-covid-19-presenting-as-acute-st-elevation-myocardial-infarction</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Patients with Covid-19 disease commonly present with symptoms related to respiratory illness, and less commonly they develop cardiovascular complications either on presentation or during the course of the disease. The mortality/​morbidity is high in these patients with cardiovascular involvement. Acute ST-elevation myocardial infarction (STEMI) is a medical emergency which needs immediate coronary re-perfusion for better patient outcomes. Here we present a patient who presented to the emergency room with acute STEMI and later tested positive for COVID-19. She was successfully treated with coronary revascularization and stent placement, and remains on the ventilator to date as she quickly developed acute respiratory distress syndrome. We need more research in Covid-19 patients with cardiovascular involvement for early diagnosis, prevention of exposure to health care workers and effective treatment.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[444] Title: </b>A Coronavirus Disease 2019 (COVID-19) Patient with Multifocal Pneumonia Treated with Hydroxychloroquine.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-03-30<​br>​
 +<​b>​Publisher:​ </​b>​Cureus<​br>​
 +<​b>​Keywords:​ </b>, 2019 novel coronavirus,​ 2019-ncov, cov, covid-19, ground-glass opacity, hydroxychloroquine,​ multifocal, pneumonia, sars-cov-2 (severe acute respiratory syndrome coronavirus -2), wuhan<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.cureus.com/​articles/​29732-a-coronavirus-disease-2019-covid-19-patient-with-multifocal-pneumonia-treated-with-hydroxychloroquine">​https://​www.cureus.com/​articles/​29732-a-coronavirus-disease-2019-covid-19-patient-with-multifocal-pneumonia-treated-with-hydroxychloroquine</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +After an outbreak in December 2019 in Wuhan, Hubei Province of China, coronavirus disease 2019 (COVID-19) has rapidly become a pandemic. The 2019 novel coronavirus (2019 nCov), now called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),​ causes a wide spectrum of illness and patients with underlying comorbidities have a high mortality. Here we present a 49-year-old male patient with comorbid conditions who presented with fever, cough, myalgia and shortness of breath for five days with likely exposure to a COVID-19 contact. A computed tomography scan of the thorax revealed multifocal bilateral ground-glass lung opacities with areas of subpleural sparing. He tested positive for SARS-CoV-2 by nucleic acid amplification. Hydroxychloroquine therapy was started, and the patient responded favorably with improvement of symptoms. Early diagnosis and self-isolation or quarantine remain key to stemming the tide of the contagion as there is a real risk of the healthcare system being overwhelmed.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[445] Title: </​b>​COVID-19 (SARS-Cov-2) and the heart - An ominous association.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-01<​br>​
 +<​b>​Publisher:​ </​b>​Cardiovascular Revascularization Medicine<​br>​
 +<​b>​Keywords:​ </​b>​Cardiovascular Medicine And Haematology,​ acute coronary syndrome, covid-19, complications,​ myocarditis,​ severe acute respiratory syndrome coronavirus 2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1553838920302566">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1553838920302566</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cardiovascular manifestations of COVID-19 are diverse and complex and include acute coronary syndrome, myocarditis masquerading as ST-segment elevation myocardial infarction, pericarditis and pericardial effusion. We present 2 cases of COVID-19 infection with myocardial involvement with distinct mechanistic pathways and outcomes. Important decision strategies such as the timing of cardiac catheterization (when indicated) and requirement of early hemodynamic support in critically ill patients are discussed.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[446] Title: </​b>​Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Case Reports in Women'​s Health<​br>​
 +<​b>​Keywords:​ </b>, acute respiratory distress syndrome, covid-19, mechanical ventilation,​ novel coronavirus disease, twin pregnancy, vertical transmission<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2214911220300503">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2214911220300503</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We present the case of a 39-year-old woman, G1P0, who had conceived twins via in-vitro fertilization,​ who presented at 27weeks of gestation with nasal congestion and dry cough for 7days. On presentation,​ her physical examination was benign, except for sinus tachycardia,​ and she was oxygenating adequately on room air. Laboratory studies were unremarkable,​ except a PCR test positive for SARS-COV2, and a CT scan of her chest showed bilateral multi-focal ground-glass opacities. A fetal non-stress test was reassuring. She was treated with intravenous fluids, ceftriaxone,​ azithromycin,​ and hydroxychloroquine. During her hospital stay, she developed progressively worsening respiratory failure, initially requiring non-invasive ventilation,​ and subsequently progressed to acute respiratory distress syndrome requiring mechanical ventilation. She then suffered from sudden hypoxemia and hemodynamic collapse, on maximal ventilatory support, prompting an emergency cesarean section at bedside. This led to rapid stabilization of hemodynamic parameters, and of her overall respiratory status. Both the twins were born prematurely,​ and one of them tested positive for SARS-COV2.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[447] Title: </​b>​Pediatric Life-Threatening Coronavirus Disease 2019 With Myocarditis.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-11<​br>​
 +<​b>​Publisher:​ </​b>​The Pediatric Infectious Disease Journal<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​pidj/​FullText/​2020/​07000/​Pediatric_Life_Threatening_Coronavirus_Disease.34.aspx">​https://​journals.lww.com/​pidj/​FullText/​2020/​07000/​Pediatric_Life_Threatening_Coronavirus_Disease.34.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We report the case of a pediatric life-threatening coronavirus disease 2019 who presented as myocarditis with heart failure. Clinicians should be aware of this severe presentation of the disease in children, possibly linked to an exaggerated inflammatory host immune response to severe acute respiratory syndrome coronavirus 2.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[448] Title: </​b>​Clinical course of COVID-19 in patients with pre-existing decompensated cirrhosis: initial report from China.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-22<​br>​
 +<​b>​Publisher:​ </​b>​Hepatology International<​br>​
 +<​b>​Keywords:​ </​b>​Colorectal Surgery, advanced chronic liver disease, covid-19, clinical characteristics,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​link.springer.com/​article/​10.1007/​s12072-020-10051-z">​https://​link.springer.com/​article/​10.1007/​s12072-020-10051-z</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: The clinical characteristics and disease course in COVID-19 patients with pre-existing decompensated cirrhosis has not been described so far. METHODS: In this case series, we report three patients with confirmed COVID-19 and pre-existing decompensated cirrhosis from three hospitals in Hubei, the epicenter of the outbreak in China. RESULT: Patient 1 was a 53-year-old man with hepatitis B virus-related cirrhosis, portal hypertension,​ and ascites. Though receiving intensive support, he died of irreversible multiple organ dysfunction syndrome 48 days after the onset of the illness. Patient 2 was a 75-year-old woman with a history of schistosomiasis-related cirrhosis, portal hypertension,​ and ascites. Her family members requested that invasive rescue measures not be undertaken, and she died of acute respiratory distress syndrome 40 days after presenting with COVID-19 infection. Patient 3 was an 87-year-old man with alcohol-related cirrhosis, portal hypertension,​ and esophageal variceal hemorrhage. He was discharged from the hospital 29 days after illness onset. CONCLUSION: The case series raise the possibility that decompensated cirrhosis may be a risk factor for a poor outcome in patients with COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[449] Title: </​b>​Successful recovery from severe COVID-19 pneumonia after kidney transplantation:​ The interplay between immunosuppression and novel therapy including tocilizumab.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-02<​br>​
 +<​b>​Publisher:​ </​b>​Transplant Infectious Disease<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-19, coronavirus,​ immunosuppression,​ kidney transplantation,​ pandemic, tocilizumab,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​tid.13334">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​tid.13334</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Although immunosuppressed patients may be more prone to SARS-CoV-2 infection with atypical presentation,​ long-term immunosuppression therapy may provide some sort of protection for severe clinical complications of COVID-19. The interaction between immunosuppression and new antiviral drugs in the treatment of transplanted patients contracting COVID-19 has not yet been fully investigated. Moreover, data regarding the optimal management of these patients are still very limited. We report a case of the successful recovery from severe COVID-19 of a kidney-transplanted patient treated with hydroxychloroquine,​ lopinavir/​ritonavir,​ steroid, and tocilizumab.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[450] Title: </​b>​Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: Case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Infection and Public Health<​br>​
 +<​b>​Keywords:​ </​b>​Public Health And Health Services, covid-19, pandemic, pneumothorax,​ subcutaneous emphysema, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1876034120304780">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1876034120304780</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome virus coronavirus 2 (SARS-CoV-2). As known, COVID-19 has become a global pandemic and serious health problem. Disease mainly affects lungs and common findings are fever cough and shortness of breath. Computerized tomography (CT) has an important role in initial evaluation and follow up of COVID-19. Main (CT) finding of the disease is bilateral extensive ground-glass opacification (GGO) with a peripheral or posterior distribution,​ mainly involving the lower lobes. In this case report, we present a pneumothorax and subcutaneous emphysema case in a patient with COVID-19. To the best of authors'​ knowledge, it is the first illustrated case of pneumothorax accompanying COVID-19 pneumonia.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[451] Title: </​b>​18F-FDG PET/CT in Hodgkin Lymphoma With Unsuspected COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-08<​br>​
 +<​b>​Publisher:​ </​b>​Clinical Nuclear Medicine<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​doi.org/​10.1097/​rlu.0000000000003143">​https://​doi.org/​10.1097/​rlu.0000000000003143</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We present an asymptomatic 70-year-old man referred for an F-FDG PET/CT for initial staging of a Hodgkin lymphoma. F-FDG PET/CT showed bilateral cervical lymphadenopathy (stage II). Incidentally,​ the CT demonstrated bilateral ground-glass opacities with low-grade F-FDG activity. CT findings were suspicious for COVID-19 pneumonitis. The COVID-19 reverse transcriptase polymerase chain reaction (RT-PCR) examination result was negative. Given the high clinical suspicion for COVID-19, the patient was isolated and repeat RT-PCR was positive at 72 hours. RT-PCR may be falsely negative in early COVID-19 disease, even with positive CT findings.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[452] Title: </​b>​Cerebral Venous Thrombosis Associated with COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-18<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Neuroradiology<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​www.ajnr.org/​content/​early/​2020/​06/​18/​ajnr.A6644">​http://​www.ajnr.org/​content/​early/​2020/​06/​18/​ajnr.A6644</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Despite the severity of coronavirus disease 2019 (COVID-19) being more frequently related to acute respiratory distress syndrome and acute cardiac and renal injuries, thromboembolic events have been increasingly reported. We report a unique series of young patients with COVID-19 presenting with cerebral venous system thrombosis. Three patients younger than 41 years of age with confirmed Severe Acute Respiratory Syndrome coronavirus 2 (SARS-Cov-2) infection had neurologic findings related to cerebral venous thrombosis. They were admitted during the short period of 10 days between March and April 2020 and were managed in an academic institution in a large city. One patient had thrombosis in both the superficial and deep systems; another had involvement of the straight sinus, vein of Galen, and internal cerebral veins; and a third patient had thrombosis of the deep medullary veins. Two patients presented with hemorrhagic venous infarcts. The median time from COVID-19 symptoms to a thrombotic event was 7 days (range, 2-7 days). One patient was diagnosed with new-onset diabetic ketoacidosis,​ and another one used oral contraceptive pills. Two patients were managed with both hydroxychloroquine and azithromycin;​ one was treated with lopinavir-ritonavir. All patients had a fatal outcome. Severe and potentially fatal deep cerebral thrombosis may complicate the initial clinical presentation of COVID-19. We urge awareness of this atypical manifestation.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[453] Title: </​b>​Case Report: A COVID-19 Patient Presenting with Mild Rhabdomyolysis.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-19<​br>​
 +<​b>​Publisher:​ </​b>​The American Journal of Tropical Medicine and Hygiene<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, , Health Sciences, Life Sciences, Medicine, Immunology and Microbiology<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​www.ajtmh.org/​content/​journals/​10.4269/​ajtmh.20-0583">​http://​www.ajtmh.org/​content/​journals/​10.4269/​ajtmh.20-0583</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The news was reported from the Wuhan region of China about a novel corona virus in the end of 2019. After spreading around the world, a pandemic was declared by the WHO. Depending on the different involvement of the disease, the most common symptoms are fever, cough, and dyspnea. However, some indeterminate symptoms that make diagnosis difficult, such as myalgia and fatigue, can also be seen alone, without the typical clinical picture. We describe a patient with COVID-19 pneumonia, the only complaint of which is myalgia, and the first diagnosis is mild rhabdomyolysis. The patient had no evidence or history other than viral infection that could explain muscle pain and also increased level of muscle enzymes. When mild rhabdomyolysis lack of myoglobinuria and complications was diagnosed, treatment-related rhabdomyolysis was also avoided as no treatment related to COVID-19 was initiated yet. Apart from the typical symptoms leading to the typical diagnosis of COVID-19 at the first admission, SARS-CoV-2 related with rhabdomyolysis should also be kept in mind.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[454] Title: </​b>​Successful Treatment of Severe COVID-19 Pneumonia With Clazakizumab in a Heart Transplant Recipient: A Case Report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​Transplantation Proceedings<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0041134520325756">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0041134520325756</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized by an overwhelming cytokine response. Various treatment strategies have been attempted. METHODS AND RESULTS: A 61-year-old man with heart transplantation in 2017 presented with fever, cough, and dyspnea, and was confirmed positive for coronavirus disease 2019 (COVID-19). Laboratory tests showed significant elevations in C-reactive protein and interleukin-6 (IL-6). Echocardiogram showed left ventricular ejection fraction 58% (with ejection fraction 57% 6 months prior). Given the lack of clear management guidelines, the patient was initially managed symptomatically. However, the patient subsequently had a rapid respiratory deterioration with worsening inflammatory markers on day 5 of admission. Tocilizumab (anti-IL-6R) was in low supply in the hospital. The patient was offered clazakizumab (anti-IL-6) for compassionate use. Patient received 25 mg intravenously x 1 dose. Within 24 hours, he showed significant improvement in symptoms, oxygen requirements,​ radiological findings, and inflammatory markers. There was a transient leukopenia that improved in 4 days. He was discharged home on day 11, with negative nasopharyngeal SARS-CoV-2 PCR as an outpatient on day 35, development of positive serum COVID-19 IgG antibody, and he continued to do well on day 60, with no heart-related symptoms. CONCLUSION: Clazakizumab is a monoclonal antibody against human IL-6, which may be helpful in inhibiting the cytokine response to SARS-CoV-2 in COVID-19. Although not yet FDA approved, it is being investigated for treatment of renal antibody-mediated rejection. Clinical trials of clazakizumab for treatment of COVID-19 are underway worldwide.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[455] Title: </​b>​Neonatal Coronavirus 2019 (COVID-19) Infection: A Case Report and Review of Literature.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-17<​br>​
 +<​b>​Publisher:​ </​b>​Cureus<​br>​
 +<​b>​Keywords:​ </b>, covid-19 in neonates, sars-cov-2, transmission in neonatal covid-19<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.cureus.com/​articles/​32203-neonatal-coronavirus-2019-covid-19-infection-a-case-report-and-review-of-literature">​https://​www.cureus.com/​articles/​32203-neonatal-coronavirus-2019-covid-19-infection-a-case-report-and-review-of-literature</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),​ has led to a global pandemic affecting 213 countries as of April 26, 2020. Although this disease is affecting all age groups, infants and children seem to be at a lower risk of severe infection, for reasons unknown at this time. We report a case of neonatal infection in New York, United States, and provide a review of the published cases. A 22-day-old, previously healthy, full-term neonate was hospitalized after presenting with a one-day history of fever and poor feeding. Routine neonatal sepsis evaluation was negative. SARS-CoV-2 polymerase chain reaction (PCR) testing was obtained, given rampant community transmission,​ which returned positive. There were no other laboratory or radiographic abnormalities. The infant recovered completely and was discharged home in two days once his feeding improved. The family was advised to self-quarantine to prevent the transmission of COVID-19. We believe that the mode of transmission was horizontal spread from his caregivers. This case highlights the milder presentation of COVID-19 in otherwise healthy, full-term neonates. COVID-19 must be considered in the evaluation of a febrile infant. Infants and children may play an important role in the transmission of COVID-19 in the community. Hence, with an understanding of the transmission patterns, parents and caregivers would be better equipped to limit the spread of the virus and protect the more vulnerable population.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[456] Title: </​b>​Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Mimicking as Pulmonary Tuberculosis in an Inmate.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-05<​br>​
 +<​b>​Publisher:​ </​b>​Cureus<​br>​
 +<​b>​Keywords:​ </b>, inmate population, prison health, pulmonary tuberculosis,​ sars-cov-2 (severe acute respiratory syndrome coronavirus -2), vulnerable group<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.cureus.com/​articles/​33565-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection-mimicking-as-pulmonary-tuberculosis-in-an-inmate">​https://​www.cureus.com/​articles/​33565-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection-mimicking-as-pulmonary-tuberculosis-in-an-inmate</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) is an emerging global infectious disease with emerging medical knowledge. Clinical presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is very variable amongst patients, and the literature about unusual presentations is growing rapidly. This lack of knowledge leads to diagnostic, therapeutic,​ and management challenges in such patients. Here, we describe a case of SARS-CoV-2 infection in a low prevalence area which was initially diagnosed and managed as pulmonary tuberculosis (TB) in a high-risk inmate population. These ambiguous presentations can lead to mismanagement of such patients resulting in potentially fatal outcomes and public health crises in confined facilities. This also highlights the significance of a high index of clinical suspicion for SARS-CoV-2 especially in high risk and vulnerable populations.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[457] Title: </​b>​Incidental typical COVID-19 appearance on the lung bases, visualized at abdominal CT for a patient that presented with abdominal pain and nausea.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-08-01<​br>​
 +<​b>​Publisher:​ </​b>​Radiology Case Reports<​br>​
 +<​b>​Keywords:​ </b>, abdominal pain, covid-19, ct abdomen, coronavirus,​ incidental findings, lung bases<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1930043320302090">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1930043320302090</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +This is a case report of a 55-year-old male patient, medically free presented to the emergency department at our hospital, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia. The patient presented with generalized abdominal pain and nausea only, without fever or any respiratory symptoms. On a computed tomography scan examination of the abdomen to rule out bowel ischemia, an incidental finding of a typical appearance of COVID-19 pneumonia was found at the visualized lung bases. The diagnosis of COVID-19 was confirmed afterward by laboratory testing. Conclusion: Typical COVID-19 findings can be suggested on lung bases at abdominal CT.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[458] Title: </​b>​Atypical Deep Cerebral Vein Thrombosis with Hemorrhagic Venous Infarction in a Patient Positive for COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-18<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Neuroradiology<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​www.ajnr.org/​content/​early/​2020/​06/​18/​ajnr.A6642">​http://​www.ajnr.org/​content/​early/​2020/​06/​18/​ajnr.A6642</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +There is growing evidence that Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) has a neurotropic and neuroinvasive potential. In particular, neurologic complications associated with the infection by SARS-CoV-2 include strokes that may result from a dysregulated inflammatory response to the infection. We report an atypical deep cerebral vein thrombosis complicated with hemorrhagic venous infarction in a patient positive for SARS-CoV-2 with no risk factors for thrombosis.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[459] Title: </​b>​COVID-19 complicated by parainfluenza co-infection in a patient with chronic lymphocytic leukemia.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1.1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-23<​br>​
 +<​b>​Publisher:​ </​b>​European Journal of Haematology<​br>​
 +<​b>​Keywords:​ </​b>​Cardiovascular Medicine And Haematology,​ covid-19, chronic lymphocytic leukemia, immunodeficiency,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ejh.13475">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ejh.13475</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The number of people suffering from the new coronavirus SARS-CoV-2 continues to rise. In SARS-CoV-2, superinfection with bacteria or fungi seems to be associated with increased mortality. The role of co-infections with respiratory viral pathogens has not yet been clarified. Here we report the course of COVID-19 in a CLL patient with secondary immunodeficiency and viral co-infection with parainfluenza.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[460] Title: </​b>​Novel Coronavirus Pneumonia Outbreak in 2019: Computed Tomographic Findings in Two Cases.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-01-01<​br>​
 +<​b>​Publisher:​ </​b>​Korean Journal of Radiology<​br>​
 +<​b>​Keywords:​ </b>, 2019 novel coronavirus,​ computed tomography, severe acute respiratory infection, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.kjronline.org/​DOIx.php?​id=10.3348/​kjr.2020.0078">​https://​www.kjronline.org/​DOIx.php?​id=10.3348/​kjr.2020.0078</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Since the 2019 novel coronavirus (2019-nCoV or officially named by the World Health Organization as COVID-19) outbreak in Wuhan, Hubei Province, China in 2019, there have been a few reports of its imaging findings. Here, we report two confirmed cases of 2019-nCoV pneumonia with chest computed tomography findings of multiple regions of patchy consolidation and ground-glass opacities in both lungs. These findings were characteristically located along the bronchial bundle or subpleural lungs.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[461] Title: </​b>​Caution should be exercised for the detection of SARS-CoV-2, especially in the elderly.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-25<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Medical Virology<​br>​
 +<​b>​Keywords:​ </​b>​Medical Microbiology,​ covid-19, gnri, rt-pcr, sars-cov-2, elderly, Health Sciences, Life Sciences, Medicine, Immunology and Microbiology<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​jmv.25796">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​jmv.25796</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +In December 2019, a pneumonia outbreak, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),​ was first identified in Wuhan, China and presented a major threat to public health. Nationwide, there were more than 70 000 confirmed cases and 2500 deaths. Most patients were elderly, with severe disease. For acute respiratory infection, reverse-transcription polymerase chain reaction (RT-PCR) is routinely used to detect causative viruses in respiratory secretions. Coronavirus RNA can be detected from nose and throat swabs, sputum and other lower respiratory tract secretions, blood, and feces. Such specimens were examined by RT-PCR. Three targets, RdRP, E, and N genes were detected, indicating samples were positive for SARS-CoV-2. After patient recovery, a chest computed tomography examination,​ combined with SARS-CoV-2 RNA detection, confirmed diagnosis. However, some recovery patients with negative RNA tests turned RNA positive. The preliminary data is about 14% of discharged patients in Guangdong reported by the Guangdong Center for Disease Control (CDC). This is an important scientific issue. If samples are positive for SARS-CoV-2 RNA, patients should be managed according to infection source. Fortunately,​ there were no close contacts of second-generation cases. We herein report six SARS-CoV-2 cases confirmed in our hospital, for the changes of results of SARS-CoV-2 RNA should attract attention. Most patients were elderly, with a low Geriatric Nutritional Risk Index (GNRI). However, the association of the phenomenon with aging and GNRI has not yet been reported in detail. Further investigations are necessary to confirm and improve these findings. Similarly, discharged patient follow-up should be strengthened.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[462] Title: </​b>​Immunosuppressive therapy maintenance in a kidney transplant recipient with SARS-CoV-2 pneumonia: A case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-08<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Transplantation<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, clinical research/​practice,​ immunosuppressive regimens, infection and infectious agents-viral,​ kidney transplantation/​nephrology,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15920">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15920</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The role of systemic inflammation is proving crucial in determining unfavorable outcome in SARS-CoV-2-infected patients. Limited data are available regarding immunosuppression management in kidney transplant recipients (KTRs) with SARS-CoV-2 pneumonia. We report a case of a 32-year-old KTR who developed SARS-CoV-2 infection and fully recovered in 15 days while maintaining standard immunosuppressive therapy.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[463] Title: </​b>​Documented early circulation of Coronavirus Disease 2019 (COVID-19) in Florida, USA, since February 2020.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-20<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Public Health<​br>​
 +<​b>​Keywords:​ </​b>​Public Health And Health Services, covid-19, case report, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​doi.org/​10.1093/​pubmed/​fdaa054">​http://​doi.org/​10.1093/​pubmed/​fdaa054</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +In this Update, we document the circulation of Coronavirus Disease 2019 (COVID-19) in Florida, USA, since February 2020. On 8th March 2020, a confirmed case of COVID-19 was notified to the Health Authority of Central Tuscany, Florence, Italy. The patient developed symptoms on 3rd March while staying in Miami where he arrived on 12th February. The case returned to Italy on 6th March and was admitted to a local hospital of Florence on 7th March with fever (38.2 degrees C/100.4 degrees F), cough and breathing difficulties. First COVID-19 cases in Florida where confirmed by the Centers for Disease Control and Prevention on 2nd March as imported cases. Therefore, this event documents COVID-19 circulation in Florida at least since mid-February 2020.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[464] Title: </​b>​Two cases of COVID-19 with positive salivary and negative pharyngeal or respiratory swabs at hospital discharge: A rising concern.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-11<​br>​
 +<​b>​Publisher:​ </​b>​Oral Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Dentistry,​ covid-19, coronavirus,​ sars-cov-2, ncov-2019, saliva, Medicine, Dentistry, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​odi.13368">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​odi.13368</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We report two cases of COVID-19 showing negative respiratory swabs but positive salivary samples at the same time. These findings rise the concern about how to manage these patients before hospital discharging,​ thus avoiding contagion among their family members or a second coronavirus wave once the lockdown is over.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[465] Title: </​b>​Clinical role of lung ultrasound for the diagnosis and monitoring of COVID-19 pneumonia in pregnant women.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-26<​br>​
 +<​b>​Publisher:​ </​b>​Ultrasound in Obstetrics & Gynecology<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, covid-19, pocus, lung ultrasound, pregnancy, Medicine, Health Professions,​ Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​uog.22055">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​uog.22055</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Lung ultrasound has recently been suggested by the Chinese Critical Care Ultrasound Study Group and Italian Academy of Thoracic Ultrasound as an accurate tool to detect lung involvement during COVID-19. Although chest Computer Tomography (CT) represents the gold standard to assess lung involvement,​ with a specificity even superior to the nasal/​pharyngeal swab for diagnosis, lung ultrasound examination can be a valid alternative to CT scan, with some advantages, particularly desirable for pregnant women. Indeed, ultrasound can be performed directly at bed side by a single operator, reducing the risk of spreading the outbreak among health professionals,​ as well as it is a radiation free exam making to be easier monitoring those patients who require serial exams. In the present study, we reported four cases of pregnant women affectd by COVID-19 infection who have been monitoring with lung ultrasound examination. All patients showed ultrasound features indicative of COVID-19 pneumonia at admission: irregular pleural lines and vertical artifacts (B-lines) were observed in all four cases, whereas patchy areas of white lung in two cases. LUS was more sensitive than chest X-ray in detecting COVID-19. Three patients had resolution of lung pathology at ultrasound after 96 h of admission. Two pregnancies are ongoing, whereas two patients had cesarean delivery with no fetal complications. PCR testing of both cord blood and newborn swabs were negative in both cases. This article is protected by copyright. All rights reserved.<​br>​
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 +----------------------------------------------------------------------<​br>​
 +<​b>​[466] Title: </​b>​Anesthetic and surgical management of tracheostomy in a patient with COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-01<​br>​
 +<​b>​Publisher:​ </​b>​Auris Nasus Larynx<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-2019, sars-cov-2, surgical management, tracheostomy,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0385814620300821">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0385814620300821</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +OBJECTIVE: The ongoing pandemic coronavirus disease-2019 (COVID-19) infection causes severe respiratory dysfunction and has become an emergent issue for worldwide healthcare. Since COVID-19 spreads through contact and droplet infection routes, careful attention to infection control and surgical management is important to prevent cross-contamination of patients and medical staff. Tracheostomy is an effective method to treat severe respiratory dysfunction with prolonged respiratory management and should be performed as a high-risk procedure METHOD: The anesthetic and surgical considerations in this case involved difficult goals of the patient safety and the management of infection among health care workers. Our surgical procedure was developed based on the previous experiences of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). RESULTS: We described the management procedures for tracheostomy in a patient with COVID-19, including the anesthesia preparation,​ surgical procedures, required medical supplies (a N95 mask or powered air purifying respirator, goggles, face shield, cap, double gloves, and a water-resistant disposable gown), and appropriate consultation with an infection prevention team. CONCLUSION: Appropriate contact, airborne precautions,​ and sufficient use of muscle relaxants are essential for performing tracheostomy in a patient with COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[467] Title: </​b>​Arterial and venous abdominal thrombosis in a 79-year-old woman with COVID-19 pneumonia.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Radiology Case Reports<​br>​
 +<​b>​Keywords:​ </b>, covid-19, ct-scan, severe acute respiratory syndrome coronavirus 2, thrombosis, coronavirus<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1930043320301588">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1930043320301588</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +As coronavirus pandemic continue to spread over the world, we have to be aware of potential complications on hospitalized patients. We report a case of a 79-year-old woman with COVID-19 pneumonia complicated by combined arterial and venous thrombosis of upper mesenteric vessels. As unenhanced chest-CT scan plays a key-role in managing the COVID-19 pandemic we should pay attention to indirect signs of thrombosis.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[468] Title: </​b>​Haemorrhagic conjunctivitis with pseudomembranous related to SARS-CoV-2.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-09-01<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Ophthalmology Case Reports<​br>​
 +<​b>​Keywords:​ </b>, covid-19, conjunctivitis,​ external ocular infections, intensive care unit, pandemic, sars-cov-2<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2451993620300876">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2451993620300876</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Purpose: To describe the multiplicity of ocular manifestations of COVID-19 patients, we report a case of pseudomembranous and hemorrhagic conjunctivitis related with SARS-CoV-2 pneumonia in a patient of intensive care unit (ICU). Observations:​ A 63-year-old male was admitted in intensive care unit (ICU), seven days after the beginning of an influenza-like symptoms, to manage an acute respiratory syndrome related with SARS-CoV-2. Chest scan showed interstitial pneumonia with "crazy paving"​ patterns. At day 19, ocular examination at the patient'​s bed described petechias and tarsal hemorrhages,​ mucous filaments and tarsal pseudomembranous. Conjunctival scrapings and swabs did not identify any bacteria or virus. To our knowledge, we described the first case of pseudomembranous conjunctivitis in a COVID-19 patient. Conclusion and importance: Considering that SARS-CoV-2 is present in tears and conjunctival secretions, external ocular infections could be factors of infectious spreading. Physicians should be aware of late (>2 weeks) ocular complications in COVID-19 patients to prevent sequelae.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[469] Title: </​b>​COVID-19 in Neonates and Infants: Progression and Recovery.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-06<​br>​
 +<​b>​Publisher:​ </​b>​The Pediatric Infectious Disease Journal<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​pidj/​FullText/​2020/​07000/​COVID_19_in_Neonates_and_Infants__Progression_and.31.aspx">​https://​journals.lww.com/​pidj/​FullText/​2020/​07000/​COVID_19_in_Neonates_and_Infants__Progression_and.31.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Between March 10, 2020 and April 17, 2020, of 8/70 (11.4%) SARS-CoV-2 positive infants that presented, 5/8 (63%) developed fever, 4/8 (50%) had lower respiratory tract involvement,​ 2/8 (25%) had neutropenia and thrombocytosis,​ and 4/8 infants (50%) were treated for suspected sepsis with broad-spectrum antibiotics. Only 1/8 (13%) required pediatric intensive care. All patients were eventually discharged home well.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[470] Title: </​b>​Analysis of complement deposition and viral RNA in placentas of COVID-19 patients.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​Annals of Diagnostic Pathology<​br>​
 +<​b>​Keywords:​ </​b>​Physiology,​ , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S109291342030071X">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S109291342030071X</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +COVID-19, the disease caused by the novel Coronavirus,​ SARS-CoV-2, is increasingly being recognized as a systemic thrombotic and microvascular injury syndrome that may have its roots in complement activation. We had the opportunity to study the placental pathology of five full-term births to COVID-19 patients. All five exhibited histology indicative of fetal vascular malperfusion characterized by focal avascular villi and thrombi in larger fetal vessels. Vascular complement deposition in the placentas was not abnormal, and staining for viral RNA and viral spike protein was negative. While all cases resulted in healthy, term deliveries, these findings indicate the systemic nature of COVID-19 infection. The finding of vascular thrombosis without complement deposition may reflect the systemic nature of COVID-19'​s procoagulant effects unrelated to systemic complement activation.<​br>​
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 +----------------------------------------------------------------------<​br>​
 +<​b>​[471] Title: </​b>​COVID-19 pneumonia in lung transplant recipients: Report of 2 cases.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-14<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Transplantation<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, clinical research/​practice,​ immunosuppressant,​ immunosuppression/​immune modulation, infection and infectious agents - viral, lung disease: infectious, lung transplantation/​pulmonology,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15993">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15993</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) has been declared pandemic since March 2020. In Europe, Italy was the first nation affected by this infection. We report anamnestic data, clinical features, and therapeutic management of 2 lung transplant recipients with confirmed COVID-19 pneumonia. Both patients were in good clinical condition before the infection and were receiving immunosuppression with calcineurin inhibitors (CNI), mycophenolate mofetil, and corticosteroids. Whereas mycophenolate mofetil was withdrawn in both cases, CNI were suspended only in the second patient. The first patient always maintained excellent oxygen saturation throughout hospitalization with no need for additional oxygen therapy. He was discharged with a satisfactory pulmonary function and a complete resolution of radiological and clinical findings. However, at discharge SARS-CoV-2 RNA could still be detected in the nasopharyngeal swab and in the stools. The second patient required mechanical ventilation,​ had a progressive deterioration of his clinical conditions, and had a fatal outcome. Further insight into SARS-CoV-2 infection is eagerly awaited to improve the outcome of transplant recipients affected by COVID-19 pneumonia.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[472] Title: </​b>​Hypogeusia as the initial presenting symptom of COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-13<​br>​
 +<​b>​Publisher:​ </​b>​BMJ Case Reports<​br>​
 +<​b>​Keywords:​ </b>, adult intensive care, ear, nose and throat/​otolaryngology,​ infectious diseases, mouth, pneumonia (respiratory medicine)<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​casereports.bmj.com/​lookup/​doi/​10.1136/​bcr-2020-236080">​https://​casereports.bmj.com/​lookup/​doi/​10.1136/​bcr-2020-236080</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +COVID-19 is the disease caused by the novel coronavirus,​ severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),​ which first arose in Wuhan, China, in December 2019 and has since been declared a pandemic. The clinical sequelae vary from mild, self-limiting upper respiratory infection symptoms to severe respiratory distress, acute cardiopulmonary arrest and death. Otolaryngologists around the globe have reported a significant number of mild or otherwise asymptomatic patients with COVID-19 presenting with olfactory dysfunction. We present a case of COVID-19 resulting in intensive care unit (ICU) admission, presenting with the initial symptom of disrupted taste and flavour perception prior to respiratory involvement. After 4 days in the ICU and 6 days on the general medicine floor, our patient regained a majority of her sense of smell and was discharged with only lingering dysgeusia. In this paper, we review existing literature and the clinical course of SARS-CoV-2 in relation to the reported symptoms of hyposmia, hypogeusia and dysgeusia.<​br>​
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 +
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oa_db/covid19_case_reports_abstracts_pg8.txt · Last modified: 2020/06/28 05:23 by bpwhite