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 +===== COVID-19 Case Reports Abstracts - Page 4 =====
  
 +[[oa_db:​covid19_case_reports_abstracts|Back to Table of Contents]]
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 +----------------------------------------------------------------------<​br>​
 +<​b>​[170] Title: </​b>​Case Report: Diagnosis of Novel Coronavirus Disease (COVID-19) versus Tropical Diseases in Pakistan.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​18.21<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-05<​br>​
 +<​b>​Publisher:​ </​b>​The American Journal of Tropical Medicine and Hygiene<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, , Health Sciences, Life Sciences, Medicine, Immunology and Microbiology<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​www.ajtmh.org/​content/​journals/​10.4269/​ajtmh.20-0356">​http://​www.ajtmh.org/​content/​journals/​10.4269/​ajtmh.20-0356</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +A 25-year-old medical student presented in Multan, Pakistan with a high fever, cough, myalgia, and diarrhea consistent with the typical signs and symptoms of novel coronavirus disease (COVID-19). The patient had traveled to high COVID-19-risk areas within Pakistan and had no significant medical and surgical history. Based on nasopharyngeal and oropharyngeal swab testing, the patient was found to be negative for COVID-19. He subsequently developed a diffuse rash and had serology consistent with dengue and measles. The patient was treated symptomatically,​ and his condition gradually improved over 7 days. This case highlights the high prevalence of many tropical diseases in low-income countries and the need for clinicians to consider alternate diagnoses in addition to testing for COVID-19 during the pandemic.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[171] Title: </b>A Postpartum Death Due to Coronavirus Disease 2019 (COVID-19) in the United States.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​18.05<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Obstetrics & Gynecology<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​pages/​results.aspx?​txtKeywords=10.1097%2fAOG.0000000000003950">​https://​journals.lww.com/​pages/​results.aspx?​txtKeywords=10.1097%2fAOG.0000000000003950</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: Limited U.S. reports of pregnant women with coronavirus disease 2019 (COVID-19) infection describe a few critical cases and no maternal mortality. CASE: A 36-year-old patient at 37 weeks of gestation presented with shortness of breath, fever, cough, and sore throat for 1 week. Within 3 hours of admission, she experienced respiratory distress, required intubation, and underwent cesarean delivery and transfer to the intensive care unit. She subsequently decompensated,​ with multiorgan failure, sepsis, and cardiopulmonary arrest within 36 hours, despite aggressive supportive care and investigational therapies. CONCLUSION: A pregnant patient with COVID-19 infection can experience a rapid onset of critical complications that may prove fatal, despite an indolent presentation. The pathogenesis leading to rapid deterioration is unknown.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[172] Title: </​b>​Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​18.05<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-18<​br>​
 +<​b>​Publisher:​ </​b>​BMC Neurology<​br>​
 +<​b>​Keywords:​ </​b>​Medicine & Public Health, covid-19, neuroinflammation,​ sars-cov-2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​bmcneurol.biomedcentral.com/​articles/​10.1186/​s12883-020-01812-2">​https://​bmcneurol.biomedcentral.com/​articles/​10.1186/​s12883-020-01812-2</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: COVID-19 is caused by the severe acute respiratory syndrome virus SARS-CoV-2. It is widely recognized as a respiratory pathogen, but neurologic complications can be the presenting manifestation in a subset of infected patients. CASE PRESENTATION:​ We describe a 78-year old immunocompromised woman who presented with altered mental status after witnessed seizure-like activity at home. She was found to have SARS-CoV-2 infection and associated neuroinflammation. In this case, we undertake the first detailed analysis of cerebrospinal fluid (CSF) cytokines during COVID-19 infection and find a unique pattern of inflammation in CSF, but no evidence of viral neuroinvasion. CONCLUSION: Our findings suggest that neurologic symptoms such as encephalopathy and seizures may be the initial presentation of COVID-19. Central nervous system inflammation may associate with neurologic manifestations of disease.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[173] Title: </​b>​Clustered Cases of Acral Perniosis: Clinical Features, Histopathology and Relationship to COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​17.93<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-12<​br>​
 +<​b>​Publisher:​ </​b>​Pediatric Dermatology<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​pde.14227">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​pde.14227</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND/​OBJECTIVES:​ There has been a recent marked increase in pediatric and adult patients presenting with purpuric acral lesions concerning for ischemia, thrombosis and necrosis in COVID-19 prevalent regions worldwide. The clinical and histopathological features and relationship to COVID-19 have not been well described. The objective of this case series is to describe the clinical features and determine the histopathologic findings and clinical implications of the clusters of acral perniosis cases identified in pediatric patients. METHODS: We describe 6 otherwise healthy adolescents - 3 siblings per family from 2 unrelated families - presented within a 48-hour period in April, 2020, with acral perniosis-like lesions in the context of over 30 similar patients who were evaluated within the same week. RESULTS: Affected patients had mild symptoms of viral upper respiratory infection (URI) or contact with symptomatic persons 1-2 weeks preceding the rash. They all presented with red to violaceous macules and dusky, purpuric plaques scattered on the mid and distal aspects of the toes. Skin biopsies performed on each of the 6 patients demonstrated near identical histopathologic findings to those of idiopathic perniosis, with a lymphocytic inflammatory infiltrate without evidence of thromboembolism or immune complex vasculitis. While SARS-CoV-2 polymerase chain reaction was negative, testing was performed 1-2 weeks after URI symptoms or sick contact exposure. CONCLUSION: We offer a clinical approach to evaluation of patients with this presentation and discuss the possibility that these skin findings represent a convalescent-phase cutaneous reaction to SARS-CoV-2 infection.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[174] Title: </​b>​Anesthetic Management of Patients Undergoing Aortic Dissection Repair With Suspected Severe Acute Respiratory Syndrome COVID-19 Infection.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​17.65<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Cardiothoracic and Vascular Anesthesia<​br>​
 +<​b>​Keywords:​ </​b>​Cardiovascular Medicine And Haematology,​ covid-19, sars-cov-2, anesthetic management, aortic dissection, infection control, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1053077020302706">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1053077020302706</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Severe acute respiratory syndrome coronavirus-2 is still active in Wuhan, China, and is spreading to the rest of the world. Recently, perioperative anesthetic management in patients with suspected or confirmed coronavirus-2 has been reported. However, little has been reported on the anesthetic management of patients undergoing aortic dissection repair in patients with suspected severe acute respiratory syndrome coronavirus-2 infection. During the outbreak in Wuhan, the authors'​ team completed 4 cases of aortic dissection repair successfully in patients with suspected severe acute respiratory syndrome coronavirus-2 infection. The purpose of the present report is to summarize current knowledge and experiences on anesthetic management in this patient population and to provide clinical practice guidelines on anesthetic management and infection prevention and control in these critically ill patients.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[175] Title: </​b>​Thromboprophylaxis in a patient with COVID-19 and severe hemophilia A on emicizumab prophylaxis.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​17.65<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-11<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Thrombosis & Haemostasis<​br>​
 +<​b>​Keywords:​ </​b>​Cardiovascular Medicine And Haematology,​ , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​jth.14954">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​jth.14954</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +COVID-19 can be associated with coagulopathy (CAC, COVID-19-associated coagulopathy) with a high prothrombotic risk based on an intense inflammatory response to viral infection leading to immunothrombosis through different procoagulant pathways[1]. Emerging evidence suggests that the use of heparin in these patients could be associated with lower mortality[2].<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[176] Title: </​b>​Thrombotic occlusive vasculopathy in skin biopsy from a livedoid lesion of a COVID-19 patient.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​16.9<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-14<​br>​
 +<​b>​Publisher:​ </​b>​British Journal of Dermatology<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​bjd.19222">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​bjd.19222</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Some authors have reported the presence of cutaneous lesions related to new COronaVirus Disease 2019 (CoViD-19) caused by SARS-CoV-2, in up to 20.4% of the cases; however, these lesions are not well characterized either clinically or histopathologically.(1) Recently, it has been highlighted the finding of congested and edematous blood vessels in the alveolar septum along with hyaline thrombi, and also in the heart, liver and kidney of autopsies of 3 patients deceased due to severe infection by SARS-CoV-2.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[177] Title: </​b>​Treatment of SARS-CoV-2 with high dose oral zinc salts: A report on four patients.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​16.9<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​International Journal of Infectious Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Microbiology,​ covid-19, case series, treatment, zinc, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1201971220304410">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1201971220304410</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus 2019 (COVID-19) is a pandemic with substantial mortality and no accepted therapy. We report here on four consecutive outpatients with clinical characteristics (CDC case definition) of and/or laboratory-confirmed COVID-19 who were treated with high dose zinc salt oral lozenges. All four patients experienced significant improvement in objective and symptomatic disease measures after one day of high dose therapy suggesting that zinc therapy was playing a role in clinical recovery. A mechanism for zinc's effects is proposed based on previously published studies on SARS- CoV-1, and randomized controlled trials assessing zinc shortening of common cold duration. The limited sample size and study design preclude a definitive statement about the effectiveness of zinc as a treatment for COVID-19 but suggest the variables to be addressed to confirm these initial findings in future trials.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[178] Title: </​b>​COVID-19 and Acute Pulmonary Embolism in Postpartum Patient.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​16.84<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-08-01<​br>​
 +<​b>​Publisher:​ </​b>​Emerging Infectious Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Medical Microbiology,​ 2019 novel coronavirus disease, covid-19, coronavirus diseases, iran, sars-cov-2, acute pulmonary embolism, pneumonia, postpartum, respiratory diseases, severe acute respiratory syndrome coronavirus 2, viruses, zoonoses, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​wwwnc.cdc.gov/​eid/​404.html?​aspxerrorpath=/​eid/​article/​26/​8/​20-1383_article">​https://​wwwnc.cdc.gov/​eid/​404.html?​aspxerrorpath=/​eid/​article/​26/​8/​20-1383_article</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We report a 36-year-old woman in Iran who sought care for left shoulder pain and cough 5 days after a scheduled cesarean section. Acute pulmonary embolism and coronavirus disease were diagnosed. Physicians should be aware of the potential for these concurrent conditions in postpartum women.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[179] Title: </​b>​Detectable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human breast milk of a mildly symptomatic patient with coronavirus disease 2019 (COVID-19).<​br><​br>​
 +<​b>​Altmetric Score: </​b>​16.83<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-30<​br>​
 +<​b>​Publisher:​ </​b>​Clinical Infectious Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Biological Sciences, covid-19, human milk, sars-cov-2, breastfeeding,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​doi.org/​10.1093/​cid/​ciaa673">​http://​doi.org/​10.1093/​cid/​ciaa673</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +SARS-CoV-2 is a novel coronavirus and causative pathogen to the pandemic illness COVID-19. Although RNA has been detected in various clinical samples, no reports to date have documented SARS-CoV-2 in human milk. This case report describes an actively breastfeeding patient with COVID-19 infection with detectable viral RNA in human milk.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[180] Title: </​b>​HEART BRAKE-An unusual cardiac manifestation of Coronavirus disease 2019 (COVID-19).<​br><​br>​
 +<​b>​Altmetric Score: </​b>​16.8<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-01<​br>​
 +<​b>​Publisher:​ </​b>​JACC:​ Case Reports<​br>​
 +<​b>​Keywords:​ </b>, bradycardia,​ covid-19, myocarditis,​ cardiomyopathy,​ complication<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2666084920304320">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2666084920304320</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +A 49-year-old male presented with worsening high-grade fevers, dry cough and shortness of breath, tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),​ and was noted to have bradycardia with intermittent high-degree AV block. However, cardiac biomarkers and echocardiography were normal, making this an unusual and interesting manifestation showing myocardial involvement of this novel coronavirus.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[181] Title: </​b>​SARS-CoV-2 can induce brain and spine demyelinating lesions.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​16.05<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-04<​br>​
 +<​b>​Publisher:​ </​b>​Acta Neurochirurgica<​br>​
 +<​b>​Keywords:​ </​b>​Interventional Radiology, covid-19, demyelinating lesions, immune response, neuro-covid,​ sars-cov-2, seizures, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​link.springer.com/​article/​10.1007/​s00701-020-04374-x">​https://​link.springer.com/​article/​10.1007/​s00701-020-04374-x</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +SARS-CoV-2 can attack the central nervous system in the early stages of infection. Headache, anosmia, and dysgeusia are common symptoms. Disturbance of consciousness and seizures can occur as complications in case of severe COVID-19. We described the case of a COVID-19 patient admitted for interstitial pneumonia and seizures. MRI showed newly diagnosed demyelinating lesions. High-dose steroid treatment allowed neurological and respiratory recovery. We speculated a delayed immune response induced by SARS-CoV-2. The virus may lead to a SIRS-like immune disorder or play a role of infective trigger. Prompt invasive treatment should be adopted to avoid hypoxic neurotoxicity and prevent CNS injuries.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[182] Title: </​b>​Invasive pulmonary aspergillosis complicating COVID-19 in the ICU - A case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​16.05<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-01<​br>​
 +<​b>​Publisher:​ </​b>​Medical Mycology Case Reports<​br>​
 +<​b>​Keywords:​ </b>, aspergillosis,​ covid-19, icu<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2211753920300300">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2211753920300300</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +It is not yet known, if critically ill COVID-19 patients are prone to fungal infections. We report a 69-year-old patient without typical risk factors for invasive pulmonary aspergillosis (IPA), who developed IPA two weeks after onset of symptoms. Our report shows that IPA may occur in critically ill COVID-19 patients.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[183] Title: </​b>​Insights for increased risk of failed fibrinolytic therapy and stent thrombosis associated with COVID-19 in ST-segment elevation myocardial infarction patients.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​15.9<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-30<​br>​
 +<​b>​Publisher:​ </​b>​Catheterization and Cardiovascular Interventions (Formerly Catheterization and Cardiovascular Diagnosis)<​br>​
 +<​b>​Keywords:​ </​b>​Cardiovascular Medicine And Haematology,​ acute myocardial infarction, antithrombotic treatment, viral infection, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​ccd.28948">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​ccd.28948</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Important health resources are dedicated worldwide to the management of COVID-19. This new disease, due to its large diffusion, may significantly hamper the prognosis of other pathologies,​ such as ST-segment elevation myocardial infarction (STEMI) because of (a) a possible direct negative impact and (b) shortage of first response medical resources and increased delays to reperfusion. We report the case of a 68-year-old man admitted for anterior STEMI and asymptomatic COVID-19. Due to extended transportation delays to a cathlab, he received intravenous fibrinolytic therapy, which failed. Reperfusion was achieved with rescue coronary angioplasty,​ but the patient experienced two episodes of acute stent thrombosis at 2- and 36-hr following admission and despite optimal medical therapy. He finally died because of cardiogenic shock. This raises concerns about a possible increase in platelet aggregability associated with COVID-19 leading to an increased risk of stent thrombosis, particularly in the context of STEMI. This pleads for the promotion of primary coronary angioplasty as the first-choice revascularization technique in this population and the use of new generation P2Y12 inhibitors. In addition, the use of GPIIb/IIIa inhibitors may be considered in every STEMI patient with COVID-19 to prevent the risk of acute stent thrombosis.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[184] Title: </​b>​COVID-19 not detected in peritoneal fluid: a case of laparoscopic appendicectomy for acute appendicitis in a COVID-19-infected patient.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​15.75<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-09<​br>​
 +<​b>​Publisher:​ </​b>​Langenbeck'​s Archives of Surgery<​br>​
 +<​b>​Keywords:​ </​b>​Abdominal Surgery, covid-19, laparoscopy,​ peritoneal fluid, safety, surgery, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​link.springer.com/​article/​10.1007/​s00423-020-01891-2">​https://​link.springer.com/​article/​10.1007/​s00423-020-01891-2</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +PURPOSE: COVID-19 greatly affected millions and affected the way we practice with heightened posture in the way we treat surgical patients. Surgical consensus guidelines are recommending caution in the use of laparoscopy for the theoretical possibility of viral transmission from aerosolization of tissue and peritoneal fluid during surgery. However, there has yet to be proof of COVID-19 being present in peritoneal fluid, justifying the consensus statements. We aim to assess the presence of COVID-19 in peritoneal fluid. METHODS: We performed a laparoscopic appendicectomy for a COVID-19-infected patient with acute appendicitis. Peritoneal fluid and peritoneal washings were collected and sent for COVID-19 PCR. RESULTS: The peritoneal fluid sample collected on entry and at the end of the operation was negative for COVID-19 on PCR. The patient had an uneventful recovery from surgery. CONCLUSIONS:​ This case revealed that COVID-19 was not detected in peritoneal fluid and peritoneal washings in a patient infected with COVID-19. This study provides novel preliminary data in the investigation of COVID-19 transmission from laparoscopy-related aerosolization.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[185] Title: </​b>​Rescue Therapy for Severe COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS) with Tissue Plasminogen Activator (tPA): A Case Series.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​15.6<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-14<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Trauma and Acute Care Surgery, The<​br>​
 +<​b>​Keywords:​ </b>, <br>
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​jtrauma/​Abstract/​9000/​Rescue_Therapy_for_Severe_COVID_19_Associated.97875.aspx">​https://​journals.lww.com/​jtrauma/​Abstract/​9000/​Rescue_Therapy_for_Severe_COVID_19_Associated.97875.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The COVID-19 pandemic has led to unprecedented stresses on modern medical systems, overwhelming the resource infrastructure in numerous countries while presenting a unique series of pathophysiologic clinical findings. Thrombotic coagulopathy is common in critically ill patients suffering from COVID-19, with associated high rates of respiratory failure requiring prolonged periods of mechanical ventilation. Here we report a case series of five patients suffering from profound, medically refractory COVID-19 associated respiratory failure who were treated with fibrinolytic therapy using tissue plasminogen activator (tPA, Alteplase). All five patients appeared to have an improved respiratory status following tPA administration:​ one patient had an initial marked improvement that partially regressed after several hours, one patient had transient improvements that were not sustained, and three patients had sustained clinical improvements following tPA administration.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[186] Title: </​b>​Parotitis-Like Symptoms Associated with COVID-19, France, March-April 2020.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​15.57<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-09-01<​br>​
 +<​b>​Publisher:​ </​b>​Emerging Infectious Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Medical Microbiology,​ covid-19, france, sars-cov-2, coronavirus disease, neck, node, parotid, parotitis, respiratory infections, severe acute respiratory syndrome coronavirus 2, viruses, zoonoses, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​wwwnc.cdc.gov/​eid/​article/​26/​9/​20-2059_article">​https://​wwwnc.cdc.gov/​eid/​article/​26/​9/​20-2059_article</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We report the clinical features of 3 patients in France who had parotitis (inflammation of the parotid salivary glands) as a clinical manifestation of confirmed coronavirus disease. Results from magnetic resonance imaging support the occurrence of intraparotid lymphadenitis,​ leading to a parotitis-like clinical picture.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[187] Title: </b>A COVID-19 Patient Who Underwent Endonasal Endoscopic Pituitary Adenoma Resection: A Case Report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​15.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-17<​br>​
 +<​b>​Publisher:​ </​b>​Neurosurgery<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, adenoma, covid-19, case report, endonasal, endoscopic, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​doi.org/​10.1093/​neuros/​nyaa147">​http://​doi.org/​10.1093/​neuros/​nyaa147</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND AND IMPORTANCE: A pituitary adenoma patient who underwent surgery in our department was diagnosed with COVID-19 and 14 medical staff were confirmed infected later. This case has been cited several times but without accuracy or entirety, we feel obligated to report it and share our thoughts on the epidemic among medical staff and performing endonasal endoscopic surgery during COVID-19 pandemic. CLINICAL PRESENTATION:​ The patient developed a fever 3 d post endonasal endoscopic surgery during which cerebrospinal leak occurred, and was confirmed with SARS-CoV-2 infection later. Several medical staff outside the operating room were diagnosed with COVID-19, while the ones who participated in the surgery were not. CONCLUSION: The deceptive nature of COVID-19 results from its most frequent onset symptom, fever, a cliche in neurosurgery,​ which makes it hard for surgeons to differentiate. The COVID-19 epidemic among medical staff in our department was deemed as postoperative rather than intraoperative transmission,​ and attributed to not applying sufficient personal airway protection. Proper personal protective equipment and social distancing between medical staff contributed to limiting epidemic since the initial outbreak. Emergency endonasal endoscopic surgeries are feasible since COVID-19 is still supposed to be containable when the surgeries are performed in negative pressure operating rooms with personal protective equipment and the patients are kept under quarantine postoperatively. However, we do not encourage elective surgeries during this pandemic, which might put patients in conditions vulnerable to COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[188] Title: </​b>​Combination of western medicine and Chinese traditional patent medicine in treating a family case of COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​15.45<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-03-13<​br>​
 +<​b>​Publisher:​ </​b>​Frontiers of Medicine<​br>​
 +<​b>​Keywords:​ </​b>​Medicine & Public Health, covid-19, chinese traditional patent medicine, shuanghuanglian oral liquid, novel coronavirus (2019-ncov)<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​link.springer.com/​article/​10.1007/​s11684-020-0757-x">​https://​link.springer.com/​article/​10.1007/​s11684-020-0757-x</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +In December 2019, an outbreak of novel coronavirus (2019-nCoV) occurred in Wuhan, Hubei Province, China. By February 14, 2020, it has led to 66 492 confirmed patients in China and high mortality up to ~2.96% (1123/37 914) in Wuhan. Here we report the first family case of coronavirus disease 2019 (COVID-19) confirmed in Wuhan and treated using the combination of western medicine and Chinese traditional patent medicine Shuanghuanglian oral liquid (SHL). This report describes the identification,​ diagnosis, clinical course, and management of three cases from a family, suggests the expected therapeutic effects of SHL on COVID-19, and warrants further clinical trials.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[189] Title: </​b>​Erythema multiforme-like lesions in children and COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​15.4<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-23<​br>​
 +<​b>​Publisher:​ </​b>​Pediatric Dermatology<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, covid-19, sars-cov-2, chilblain, erythema multiforme, pernio, skin, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​pde.14246">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​pde.14246</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +During examination of cases of chilblains in children and adolescents,​ we identified four patients who also showed skin lesions similar to erythema multiforme (EM). They had no other known triggers for EM. One of them had a positive PCR for SARS-CoV-2, while the other 3 were negative. Skin biopsies from two patients showed features not typical of EM, such as deep perivascular and perieccrine infiltrate and absence of necrosis of keratinocytes. Immunohistochemistry for SARS-CoV/​SARS-CoV-2 spike protein showed granular positivity in endothelial cells and epithelial cells of eccrine glands in both biopsies. All patients had an excellent outcome, and had minimal or no systemic symptoms. The coincidence of EM, a condition commonly related to viruses, and chilblains in the setting of COVID-19, as well as the positivity for SARS-CoV/​SARS-CoV-2 spike protein by immunohistochemistry strongly suggest a link between EM-like lesions and SARS-CoV-2.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[190] Title: </​b>​Acute Symptomatic Seizures in Critically Ill Patients with COVID-19: Is There an Association?<​br><​br>​
 +<​b>​Altmetric Score: </​b>​14.9<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-28<​br>​
 +<​b>​Publisher:​ </​b>​Neurocritical Care<​br>​
 +<​b>​Keywords:​ </​b>​Intensive / Critical Care Medicine, coronavirus,​ seizures, status epilepticus,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​link.springer.com/​article/​10.1007/​s12028-020-01006-1">​https://​link.springer.com/​article/​10.1007/​s12028-020-01006-1</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: The coronavirus disease of 2019 (COVID-19) emerged as a global pandemic. Historically,​ the group of human coronaviruses can also affect the central nervous system leading to neurological symptoms; however, the causative mechanisms of the neurological manifestations of COVID-19 disease are not well known. Seizures have not been directly reported as a part of COVID-19 outside of patients with previously known brain injury or epilepsy. We report two cases of acute symptomatic seizures, in non-epileptic patients, associated with severe COVID-19 disease. CASE PRESENTATIONS:​ Two advanced-age,​ non-epileptic,​ male patients presented to our northeast Ohio-based health system with concern for infection in Mid-March 2020. Both had a history of lung disease and during their hospitalization tested positive for SARS-CoV-2. They developed acute encephalopathy days into their hospitalization with clinical and electrographic seizures. Resolution of seizures was achieved with levetiracetam. DISCUSSION: Patients with COVID-19 disease are at an elevated risk for seizures, and the mechanism of these seizures is likely multifactorial. Clinical (motor) seizures may not be readily detected in this population due to the expansive utilization of sedatives and paralytics for respiratory optimization strategies. Many of these patients are also not electrographically monitored for seizures due to limited resources, multifactorial risk for acute encephalopathy,​ and the risk of cross-contamination. Previously, several neurological symptoms were seen in patients with more advanced COVID-19 disease, and these were thought to be secondary to multi-system organ failure and/or disseminated intravascular coagulopathy-related brain injury. However, these patients may also have an advanced breakdown of the blood-brain barrier precipitated by pro-inflammatory cytokine reactions. The neurotropic effect and neuroinvasiveness of SARS-Coronavirus-2 have not been directly established. CONCLUSIONS:​ Acute symptomatic seizures are possible in patients with COVID-19 disease. These seizures are likely multifactorial in origin, including cortical irritation due to blood-brain barrier breakdown, precipitated by the cytokine reaction as a part of the viral infection. Patients with clinical signs of seizures or otherwise unexplained encephalopathy may benefit from electroencephalography monitoring and/or empiric anti-epileptic therapy. Further studies are needed to elucidate the risk of seizures and benefit of monitoring in this population.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[191] Title: </​b>​Early virus clearance and delayed antibody response in a case of COVID-19 with a history of co-infection with HIV-1 and HCV.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​14.5<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-09<​br>​
 +<​b>​Publisher:​ </​b>​Clinical Infectious Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Biological Sciences, antibody, covid-19, hcv, hiv-1, sars-cov-2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​doi.org/​10.1093/​cid/​ciaa408">​http://​doi.org/​10.1093/​cid/​ciaa408</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The effect of host immune status on SARS-CoV-2 infection remains unknown. Here, we report the first case of COVID-19 with HIV-1 and HCV co-infection,​ who showed a persistently negative SARS-CoV-2 RNA test, but delayed antibody response in the plasma. This case highlights the influence of HIV-1-induced immune dysfunction on the early SARS-CoV-2 clearance.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[192] Title: </​b>​Varying Presentations of COVID-19 in Young Heart Transplant Recipients: A Case Series.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​14.4<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-15<​br>​
 +<​b>​Publisher:​ </​b>​Pediatric Transplantation<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​petr.13780">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​petr.13780</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: Immunosuppression is considered a risk factor for more severe clinical presentation of COVID-19. Limited data regarding clinical outcome exist in adults, whereas very little is known about the spectrum of the disease in pediatric heart transplant recipients. METHODS: We retrospectively reviewed the charts of young heart transplant patients from our tertiary care center during the coronavirus pandemic in New York City and identified patients infected with SARS-CoV-2. RESULTS: We present four cases with COVID-19 disease and elaborate on their presentation and clinical course. CONCLUSIONS:​ Although far from conclusive and limited by the small sample size and selection bias, these cases demonstrate mild and self-limited disease despite immunosuppressive therapy and various comorbidities that are expected to increase the severity of the clinical picture based on extrapolation from the adult experience with this novel disease.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[193] Title: </​b>​Evolution of severe acute respiratory syndrome coronavirus 2 RNA test results in a patient with fatal coronavirus disease 2019: a case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​14.35<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Human Pathology<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, coronavirus,​ multiorgan failure, sars-cov-2, secondary bacterial infection, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0046817720300873">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0046817720300873</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +A 65-year-old man was hospitalized owing to fever (38.6 degrees C) and dry cough since 4 days. He visited Wuhan 8 days ago. At admission, nasopharyngeal swab samples were taken, and polymerase chain reaction analysis confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA positivity. On day 9, after admission, the chest computed tomography scan showed diffuse ground-glass shadows in the patient'​s bilateral lungs. On day 11, his respiratory symptoms worsened. Subsequently,​ type I respiratory failure was diagnosed, coinciding with kidney injury, and subsequently,​ type II respiratory failure occurred, coupled with multiorgan failure including the heart and liver. However, the patient'​s constitution worsened although SARS-CoV-2 tests were negative since day 13. He died on day 21. Lung biopsy showed areas of diffuse alveolar damage, characterized by extensive acute alveolitis with numerous intra-alveolar neutrophil, lymphocyte, and macrophage infiltrations. Microthrombi were seen in the dilated pulmonary capillaries. Immunohistochemistry staining for SARS-CoV-2 N protein was negative. Taken together, the patient died of multiorgan failure although the SARS-CoV-2 infection was cleared already, implicating that for disease worsening, no active SARS-CoV-2 infection is required.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[194] Title: </​b>​Rehospitalization of a Recovered Coronavirus Disease 19 (COVID-19) Child With Positive Nucleic Acid Detection.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​14.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​The Pediatric Infectious Disease Journal<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​pidj/​FullText/​2020/​06000/​Rehospitalization_of_a_Recovered_Coronavirus.21.aspx">​https://​journals.lww.com/​pidj/​FullText/​2020/​06000/​Rehospitalization_of_a_Recovered_Coronavirus.21.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Since December 2019, novel coronavirus-infected pneumonia (coronavirus disease 19) occurred in Wuhan and rapidly spread throughout China and beyond. During this period, increasing of reports found that several recovered patients from different hospitals showed positive results of nucleic acid test again soon after discharge. However, little attention has been paid to recovered children. Herein, we reported a case of 8-year-old recovered child, who was rehospitalized again because of unexplained fever.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[195] Title: </​b>​COVID-19 in posttransplant patients-report of 2 cases.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​13.45<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-17<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Transplantation<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, covid-19, coronavirus,​ transplantation,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15896">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15896</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus Disease 2019 (COVID-19) has become a pandemic since March 2020. We describe here 2 cases of COVID-19 infection in a posttransplant setting. First one is a 59-year-old renal transplant recipient; the second is a 51-year-old allogeneic bone marrow transplant recipient. Both patients were on immunosuppressant therapy and had stable graft function before COVID-19 infection. After the diagnosis of COVID-19, immunosuppressive agents were discontinued and methylprednisolone with prophylactic antibiotics were initiated, however, the lung injury progressed. The T cells were extremely low in both patients after infection. Both patients died despite the maximal mechanical ventilatory support. Therefore, the prognosis of COVID-19 pneumonia following transplantation is not optimistic and remains guarded. Lower T cell count may be a surrogate for poor outcome.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[196] Title: </​b>​COVID-19 occurring during Natalizumab treatment: a case report in a patient with extended interval dosing approach.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​13.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​Multiple Sclerosis and Related Disorders<​br>​
 +<​b>​Keywords:​ </b>, coronavirus,​ covid 19, extended interval dosing, multiple sclerosis, natalizumab,​ relapsing remitting multiple sclerosis<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2211034820302418">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2211034820302418</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: The novel Coronavirus SARS-CoV-2, which was identified after a recent outbreak in Wuhan, China, in December 2019, has generated a global pandemic impacting over 200 countries around the world. Recent reports suggest that ACE2, which is the target protein to invade the host, has a ubiquitous presence in human organs, including lung parenchyma, gastrointestinal tract, nasal mucosa, renal and urinary tract, airway epithelia, lymphoid tissues, reproductive organs, vascular endothelium and neurons. In this scenario, neurologists are particularly involved into considering even more specific therapeutic strategies according to the available data during the pandemic. In particular, MS patients are usually receiving disease-modifying therapies (DMTs) with immunosuppressant or immunomodulatory effects, which increase the risk of infections and morbidity, compared with the general population. Development of PML or other serious opportunistic infections during treatment with natalizumab forces to consider whether de-risking strategies are needed in this particular context and how to manage a high-efficacy treatment. METHODS: In this paper we report on a patient treated with natalizumab for relapsing MS who developed COVID-19 and recovered in a few days without complications. RESULTS: After recovery natalizumab has been administered in the window of the extended interval dosing (EID), without reporting any worsening or new symptoms. DISCUSSION: This case supports the opportunity to avoid discontinuing or delaying the retreatment over 8 weeks in patients recovered from a recent COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[197] Title: </​b>​COVID-19 in an HIV-positive Kidney Transplant Recipient.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​13.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-26<​br>​
 +<​b>​Publisher:​ </​b>​Transplant Infectious Disease<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-19, human immunodeficiency virus, kidney transplantation,​ severe acute respiratory syndrome coronavirus-2,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​tid.13338">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​tid.13338</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We report a case of a 50-year-old male with a history of HIV and kidney transplant who presented with SARS-CoV-2. We also present a review of COVID-19 cases in kidney transplant recipients.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[198] Title: </​b>​Medically unexplained symptoms in the times of Covid-19 pandemic: a case-report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​13.2<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-01<​br>​
 +<​b>​Publisher:​ </​b>​Brain,​ Behavior, & Immunity - Health<​br>​
 +<​b>​Keywords:​ </b>, 2019-ncov, anxiety, child and adolescent psychiatry, coronavirus,​ obsessive compulsive symptoms, somatic symptom disorder<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2666354620300387">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2666354620300387</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +In early 2020, a novel coronavirus (SARS-CoV-2) leading to a potentially fatal condition was discovered. Since then, the 2019 coronavirus disease (COVID-19) has spread worldwide becoming a pandemic. Beyond the risks strictly related to the infection, concerns have been expressed for the psychological impact that COVID-19 may have, especially on vulnerable individuals with pre-existing mental health conditions. Somatic symptom disorder (SSD) is characterized by a dysfunctional preoccupation with physical symptoms leading to excessive and unnecessary healthcare utilization. Despite being quite common, such condition remains underrecognized. We report a detailed clinical case of a 16 years old adolescent, who presented with a history suggestive of COVID-19 infection and associated psychological distress. Despite testing negative for the presence of SARS-CoV-2, his extreme and persisting health preoccupations required an inpatient admission to the Child and Adolescent Neuropsychiatric Unit. He responded rapidly to a low dose of antipsychotic and an antidepressant. Based on his medical history and current presentation,​ he received a diagnosis of SSD. When COVID-19-like symptoms occur, we highlight the importance of differentially diagnosing a possible exacerbation of a pre-existing SSD, triggered by fear of being infected. This may help preventing further burden to the healthcare system.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[199] Title: </​b>​COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​13.05<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-13<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Transplantation<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, clinical research/​practice,​ immunosuppressant - fusion proteins and monoclonal antibodies, infection and infectious agents - viral, infectious disease, kidney transplantation/​nephrology,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15935">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15935</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab,​ after immunosuppression reduction; the patient did not require mechanical ventilation. During the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, transplant clinicians should be readily informed about new cases of COVID-19 pneumonia in solid organ transplant recipients, with focus on therapeutic strategies employed and their outcome.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[200] Title: </​b>​Unexpected BP Sensitivity to Angiotensin II in a Patient With Coronavirus Disease 2019, ARDS, and Septic Shock.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​13<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-01<​br>​
 +<​b>​Publisher:​ </​b>​CHEST<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-19, sars-cov-2, angiotensin ii, septic shock, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0012369220307479">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0012369220307479</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We report the case of an 88-year-old man with coronavirus disease 2019 (COVID-19) who presented with ARDS and septic shock. The patient had exquisite BP sensitivity to low-dose angiotensin II (Ang-2), allowing for rapid liberation from high-dose vasopressors. We hypothesize that sensitivity to Ang-2 might be related to biological effect of severe acute respiratory syndrome coronavirus 2 infection. The case is suggestive of a potential role for synthetic Ang-2 for patients with COVID-19 and septic shock. Further studies are needed to confirm our observed clinical efficacy.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[201] Title: </​b>​Asymptomatic COVID-19: What the Neuroradiologist Needs to Know about Pulmonary Manifestations.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.9<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-14<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Neuroradiology<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​www.ajnr.org/​content/​41/​6/​966">​http://​www.ajnr.org/​content/​41/​6/​966</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) is an infectious disease with a high asymptomatic incidence. Asymptomatic infections within a population will inevitably lead to diagnosis via unrelated medical imaging. We report the case of an asymptomatic patient undergoing a spine CT examination for trauma who was incidentally found to have lung abnormalities later confirmed to be COVID-19. We aim to familiarize neuroradiologists with the spectrum of COVID-19 pulmonary manifestations that are likely to be observed on neck and spine CT imaging.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[202] Title: </​b>​Fulminant Acute Kidney Injury in a Young Patient with Novel Coronavirus 2019.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.81<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-06<​br>​
 +<​b>​Publisher:​ </​b>​CardioRenal Medicine<​br>​
 +<​b>​Keywords:​ </b>, ace2 receptors, acute kidney injury, continuous veno-venous hemofiltration,​ coronavirus disease 2019<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.karger.com/​Article/​FullText/​508179">​https://​www.karger.com/​Article/​FullText/​508179</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) is a global pandemic affecting more than 200 countries and 180,000 cases in the United States. While the outbreak began in China, the number of cases outside of China exceeded those in China on March 15, 2020 and are currently rising at an exponential rate. The number of fatalities in the United States are expected to exceed more than Italy and China. The disease is characterized predominantly as an acute respiratory illness. However, preliminary data suggests that kidney is a target for the virus and deterioration of renal function was associated with poor outcomes including in-hospital mortality. We pre-sent a report of a patient with COVID-19 who presented with acute onset of symptoms and normal renal function at baseline but rapidly deteriorated resulting in death. The timing of decline in renal function correlated with his worsening clinical status. He was started on continuous veno-venous hemofiltration without signs of clinical benefit. We also present the possible mechanisms for acute kidney injury in these patients. We performed a review of the emerging literature by searching PubMed, Google Scholar, and EMBASE for studies and/or case series published on this topic. Acute kidney injury might help risk stratify critically ill patients on a fatal course of COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[203] Title: </​b>​Anosmia and Ageusia as the Only Indicators of Coronavirus Disease 2019 (COVID-19).<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.67<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-01<​br>​
 +<​b>​Publisher:​ </​b>​Cureus<​br>​
 +<​b>​Keywords:​ </b>, ageusia, anosmia, atypical coronavirus,​ coronavirus,​ covid-19, loss of smell, loss of taste, novel coronavirus<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.cureus.com/​articles/​30810-anosmia-and-ageusia-as-the-only-indicators-of-coronavirus-disease-2019-covid-19">​https://​www.cureus.com/​articles/​30810-anosmia-and-ageusia-as-the-only-indicators-of-coronavirus-disease-2019-covid-19</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The patient is a 60-year-old woman with a history of vertigo and seasonal allergies who presented to the hospital with the chief complaint of headache. Radiological findings were negative for intracranial abnormalities. The headache was due to trigeminal neuralgia. She had concurrent complaints of anosmia and ageusia without fever, respiratory symptoms, or obvious risk factors. However, it was determined to test the patient for coronavirus disease 2019 (COVID-19) infection despite extremely low clinical suspicion. Unfortunately,​ she was found to be COVID-19 positive after she was discharged from the hospital while she remained asymptomatic. There is currently a lack of published case reports describing COVID-19 patients with the sole symptoms of anosmia and ageusia in the United States of America.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[204] Title: </​b>​COVID-19 infection and treatment with hydroxychloroquine cause severe haemolysis crisis in a patient with glucose-6-phosphate dehydrogenase deficiency.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.6<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-07<​br>​
 +<​b>​Publisher:​ </​b>​European Journal of Haematology<​br>​
 +<​b>​Keywords:​ </​b>​Cardiovascular Medicine And Haematology,​ covid-19, g6pd deficiency, sars-cov-2, coronavirus,​ haemolysis, hydroxychloroquine,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ejh.13432">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ejh.13432</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited genetic disorder caused by red cell enzymatic defects and is associated with haemolytic crisis when patients are exposed to oxidative agents (fava beans, drugs, infections). Hydroxychloroquine is suspected to trigger haemolytic crisis in G6PD-deficient patients, and off-label administration of this drug to patients infected with the novel coronavirus (SARS-CoV-2) could cause concern. We report here the first case of severe haemolytic crisis in a patient with G6PD deficiency, initiated by severe COVID-19 infection and hydroxychloroquine use. With worldwide spread of COVID-19, especially in regions with a high prevalence of G6PD deficiency, our case should alert physicians to this possible correlation.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[205] Title: </​b>​Guillain-Barre Syndrome associated with SARS-CoV-2 infection.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.43<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-01-01<​br>​
 +<​b>​Publisher:​ </​b>​IDCases<​br>​
 +<​b>​Keywords:​ </b>, covid-19, guillain-barre syndrome, sars-cov-2<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2214250920300792">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2214250920300792</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We present a case of Guillain- Barre Syndrome (GBS) in a patient with confirmed COVID-19 infection. GBS in commonly encountered after an antecedent trigger, most commonly an infection. To date, only one case of GBS associated with this infection has been described. Clinicians should consider this entity since it may warrant appropriate isolation precautions especially in a patient who may not present primarily with typical constitutional and respiratory symptoms associated with COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[206] Title: </​b>​Reactivation of SARS-CoV-2 after Recovery.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.4<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-23<​br>​
 +<​b>​Publisher:​ </​b>​Pediatrics International<​br>​
 +<​b>​Keywords:​ </b>, covid-19, sars-cov-2, pediatrics, reactivation,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ped.14312">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ped.14312</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) has now spread worldwide as a global pandemic.(1) We report on an 8-year-old boy who might be a patient with reactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a family cluster.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[207] Title: </​b>​Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19).<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.3<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Obstetrics & Gynecology<​br>​
 +<​b>​Keywords:​ </​b>​Paediatrics And Reproductive Medicine, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​pages/​results.aspx?​txtKeywords=10.1097%2fAOG.0000000000003949">​https://​journals.lww.com/​pages/​results.aspx?​txtKeywords=10.1097%2fAOG.0000000000003949</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by physiologic changes and other pregnancy considerations and requires balancing maternal and fetal well-being. CASE: We report the case of a patient at 28 weeks of gestation with acute respiratory distress syndrome (ARDS) from COVID-19 infection, whose deteriorating respiratory condition prompted delivery. Our patient'​s oxygenation and respiratory mechanics improved within hours of delivery, though she required prolonged mechanical ventilation until postpartum day 10. Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative. CONCLUSION: We describe our multidisciplinary management of a preterm pregnant patient with ARDS from COVID-19 infection and her neonate.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[208] Title: </​b>​Recovery of severely ill COVID-19 patients by intravenous immunoglobulin (IVIG) treatment: A case series.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.2<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-09-01<​br>​
 +<​b>​Publisher:​ </​b>​Virology<​br>​
 +<​b>​Keywords:​ </​b>​Biological Sciences, covid-19, ivig, improvement,​ Life Sciences, Immunology and Microbiology<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0042682220300933">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0042682220300933</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +INTRODUCTION:​ During the recent months, COVID-19 has turned to a global crisis claiming high mortality and morbidity among populations. Despite the high prevalence of the disease, it has currently no definitive treatment. We here reported the effects of intravenous immunoglobulin (IVIG) administration in severely ill COVID-19 patients diagnosed based on PCR and radiology tests. CASE PRESENTATION:​ Five severely ill COVID-19 patients in whom standard treatments failed were administrated with IVIG which prevented the deterioration of clinical symptoms. All the patients were treated with high-dose IVIG (0.3-0.5 g/kg) for 5 consecutive days so that no patient would receive lower than 25 g of the drug. All the patients showed a desirable therapeutic response and were discharged from the hospital with a stable clinical condition after being recovered. CONCLUSION: Treatment with IVIG at the therapeutic dose of 0.3-0.5 g/kg can improve the clinical condition and O2 saturation and prevent the progression of pulmonary lesions in COVID-19 patients with severe symptoms in whom standard treatments have failed.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[209] Title: </​b>​Case Report: The First Case of COVID-19 in Bhutan.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.13<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-03<​br>​
 +<​b>​Publisher:​ </​b>​The American Journal of Tropical Medicine and Hygiene<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, , Health Sciences, Life Sciences, Medicine, Immunology and Microbiology<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​www.ajtmh.org/​content/​journals/​10.4269/​ajtmh.20-0259">​http://​www.ajtmh.org/​content/​journals/​10.4269/​ajtmh.20-0259</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The initial cases of novel coronavirus disease-19 (COVID-19) in a country are of utmost importance given their impact on healthcare providers, the country'​s preparedness response, and the initial molding of the public perception toward this pandemic. In Bhutan, the index case was a 76-year-old immunocompromised man who had traveled from the United States and entered Bhutan as a tourist. He presented initially with vague gastrointerestinal symptoms and later a cough. His atypical presentation led to a delay in diagnosis, but ultimately he was isolated and tested. On confirming the diagnosis of COVID-19, the patient was isolated in a separate hospital with a dedicated medical care team. All contacts were traced and quarantined. The patient'​s respiratory status deteriorated despite broad-spectrum antivirals, antibiotics,​ and intensive supportive care. He required intubation and was given a trial of intravenous immunoglobulin to modulate his likely aberrant immune response. Subsequently,​ the patient'​s clinical status improved, and after 8 days of hospitalization,​ he was transferred out of the country, where he recovered. This was a learning experience for the treating medical staff, the government, and the people of Bhutan.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[210] Title: </​b>​Management of Acute Severe Ulcerative Colitis in a Pregnant Woman With COVID-19 Infection: A Case Report and Review of the Literature.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​12.1<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-12<​br>​
 +<​b>​Publisher:​ </​b>​Inflammatory Bowel Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-19, coronavirus,​ cyclosporine,​ inflammatory bowel disease, pregnancy, ulcerative colitis, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​doi.org/​10.1093/​ibd/​izaa109">​http://​doi.org/​10.1093/​ibd/​izaa109</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +First detected in Wuhan, China, the novel 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped RNA beta-coronavirus responsible for an unprecedented,​ worldwide pandemic caused by COVID-19. Optimal management of immunosuppression in inflammatory bowel disease (IBD) patients with COVID-19 infection currently is based on expert opinion, given the novelty of the infection and the corresponding lack of high-level evidence in patients with immune-mediated conditions. There are limited data regarding IBD patients with COVID-19 and no data regarding early pregnancy in the era of COVID-19. This article describes a patient with acute severe ulcerative colitis (UC) during her first trimester of pregnancy who also has COVID-19. The case presentation is followed by a review of the literature to date on COVID-19 in regard to inflammatory bowel disease and pregnancy, respectively.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[211] Title: </​b>​Successful treatment of severe COVID-19 pneumonia in a liver transplant recipient.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.85<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-19<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Transplantation<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, clinical research/​practice,​ immunosuppressant,​ infection and infectious agents - viral, infectious disease, liver transplantation/​hepatology,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15901">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15901</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) pandemic spreads rapidly and may be an increasing challenge for transplant community. Clinical data on COVID-19 infection in transplant population is very limited. Herein we presented the clinical course and outcome of a 50-year-old male post liver transplantation who contracted COVID-19, with subsequent infection of his wife. The process of illness was representative. A therapeutic regime with temporary immunosuppression withdrawal and systemic low-dose corticosteroid as principle was involved in the management of the patient which made him recover from severe COVID-19 pneumonia.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[212] Title: </​b>​The index case of SARS-CoV-2 in Scotland.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.78<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Infection<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, communicable diseases, emerging, coronavirus,​ respiratory tract infections, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0163445320301481">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0163445320301481</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Since its identification in December 2019, SARS-CoV-2 has infected 125,048 persons globally with cases identified in 118 countries across all continents. We report on the Scottish index case of SARS-CoV-2 infection, the virus causing COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[213] Title: </​b>​Identification of Kidney Transplant Recipients with Coronavirus Disease 2019.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.78<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​European Urology<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, clinical feature, coronavirus disease 2019, kidney transplant recipient, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0302283820302050">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0302283820302050</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Coronavirus disease 2019 (COVID-19) is a novel and lethal infectious disease, posing a threat to global health security. The number of cases has increased rapidly, but no data concerning kidney transplant (KTx) recipients infected with COVID-19 are available. To present the epidemiological,​ clinical, and therapeutic characteristics of KTx recipients infected with COVID-19, we report on a case series of five patients who were confirmed as having COVID-19 through nucleic acid testing (NAT) from January 1, 2020 to February 28, 2020. The most common symptoms on admission to hospital were fever (five patients, 100%), cough (five patients, 100%), myalgia or fatigue (three patients, 60%), and sputum production (three patients, 60%); serum creatinine or urea nitrogen levels were slightly higher than those before symptom onset. Four patients received a reduced dose of maintenance immunosuppressive therapy during hospitalization. As of March 4, 2020 NAT was negative for COVID-19 in three patients twice in succession, and their computed tomography scans showed improved images. Although greater patient numbers and long-term follow-up data are needed, our series demonstrates that mild COVID-19 infection in KTx recipients can be managed using symptomatic support therapy combined with adjusted maintenance immunosuppressive therapy.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[214] Title: </​b>​Alert for non-respiratory symptoms of Coronavirus Disease 2019 (COVID-19) patients in epidemic period: A case report of familial cluster with three asymptomatic COVID-19 patients.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.68<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-03-19<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Medical Virology<​br>​
 +<​b>​Keywords:​ </​b>​Medical Microbiology,​ covid-19, family cluster, incubation period, Health Sciences, Life Sciences, Medicine, Immunology and Microbiology<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​resolve/​doi?​DOI=10.1002/​jmv.25776">​https://​onlinelibrary.wiley.com/​resolve/​doi?​DOI=10.1002/​jmv.25776</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +At present, Coronavirus Disease 2019 (COVID-19) is rampaging around the world. However, asymptomatic carriers intensified the difficulty of prevention and management. Here we reported the screening, clinical feathers, and treatment process of a family cluster involving three COVID-19 patients. The discovery of the first asymptomatic carrier in this family cluster depends on the repeated and comprehensive epidemiological investigation by disease control experts. In addition, the combination of multiple detection methods can help clinicians find asymptomatic carriers as early as possible. In conclusion, the prevention and control experience of this family cluster showed that comprehensive rigorous epidemiological investigation and combination of multiple detection methods were of great value for the detection of hidden asymptomatic carriers. This article is protected by copyright. All rights reserved.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[215] Title: </​b>​SARS Cov-2 infection in a renal-transplanted patient: A case report.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.55<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-10<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Transplantation<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, clinical research/​practice,​ immunosuppressant - calcineurin inhibitor: tacrolimus, infection and infectious agents - viral, infectious disease, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15902">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15902</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The clinical manifestation of COVID-19 can vary from an asymptomatic course to ARDS requiring invasive mechanical ventilation and extracorporeal membrane oxygenation. A kidney transplanted patient infected with SARS CoV-2 infection showed a mild disease despite immune suppression. It is possible that Immunosuppression can "be protective"​ as the cytokine storm is an important factor in the disease story. Despite the good outcome reported in the present case report, is remains of vital importance the solid organ transplant patients use precautions in order to avoid the infection.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[216] Title: </​b>​COVID-19 with spontaneous pneumothorax,​pneumomediastinum and subcutaneous emphysema.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.45<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-25<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Travel Medicine<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, 2019-ncov, sars-cov-2, coronavirus,​ pandemic, pneumonia, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​http://​doi.org/​10.1093/​jtm/​taaa062">​http://​doi.org/​10.1093/​jtm/​taaa062</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We present a case of COVID-19 pneumonia associated with spontaneous pneumothorax,​ pneumomediastinum and subcutaneous emphysema.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[217] Title: </​b>​Are Type 1 Interferons treatment in Multiple Sclerosis as a potential therapy against COVID-19?<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.4<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Multiple Sclerosis and Related Disorders<​br>​
 +<​b>​Keywords:​ </b>, <br>
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2211034820302728">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2211034820302728</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Background: : The Coronavirus (COVID-19), (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)) has been spreading worldwide since its first identification in China. It has been speculated that patients with comorbidities and elderly patients could be at high risk for the pandemic reasoned respiratory insufficiency and death. At first, it was thought that the patients who use immunmodulator therapy could be even at higher risks of disease complications. However, it has been also speculated about that using immunmodulators could be an advantage for the clinical prognosis. Therefore, several immunmodulators are currently being tested as potential treatment for COVID-19. Methods: : In this paper we report on a patient that has been treated with type 1 interferon for multiple sclerosis who developed COVID-19. Results: : Despite using immunmodulator,​ the symptoms of the patient at hospitalization were mild and he did not show elevated D-dimer, and there was no lymphopenia. He was discharged to home-quarantine with no symptoms. Discussion: : This report supports the idea of using type 1 interferon in the treatment could be effective in COVID-19 affected patients.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[218] Title: </​b>​Are type 1 interferons treatment in Multiple Sclerosis as a potential therapy against COVID-19?<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.4<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-07-01<​br>​
 +<​b>​Publisher:​ </​b>​Multiple Sclerosis and Related Disorders<​br>​
 +<​b>​Keywords:​ </b>, <br>
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2211034820302728">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S2211034820302728</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +BACKGROUND: The Coronavirus (COVID-19), (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)) has been spreading worldwide since its first identification in China. It has been speculated that patients with comorbidities and elderly patients could be at high risk for the pandemic reasoned respiratory insufficiency and death. At first, it was thought that the patients who use immunmodulator therapy could be even at higher risks of disease complications. However, it has been also speculated about that using immunmodulators could be an advantage for the clinical prognosis. Therefore, several immunmodulators are currently being tested as potential treatment for COVID-19. METHODS: In this paper we report on a patient that has been treated with type 1 interferon for multiple sclerosis who developed COVID-19. RESULTS: Despite using immunmodulator,​ the symptoms of the patient at hospitalization were mild and he did not show elevated D-dimer, and there was no lymphopenia. He was discharged to home-quarantine with no symptoms. DISCUSSION: This report supports the idea of using type 1 interferon in the treatment could be effective in COVID-19 affected patients.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[219] Title: </​b>​Fatal outcome in a liver transplant recipient with COVID-19.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.38<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-04<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Transplantation<​br>​
 +<​b>​Keywords:​ </​b>​Medical And Health Sciences, clinical research/​practice,​ immunosuppressant,​ immunosuppression/​immune modulation, infection and infectious agents, infection and infectious agents - viral, liver transplantation/​hepatology,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15909">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​ajt.15909</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Liver injury is common in patients with COVID-19, but little is known about its clinical presentation and severity in the context of liver transplant. We describe a case of COVID-19 in a patient who underwent transplant 3 years ago for hepatocellular carcinoma. The patient came to clinic with symptoms of respiratory disease; pharyngeal swabs for severe acute respiratory syndrome coronavirus 2 were positive. His disease progressed rapidly from mild to critical illness and was complicated by several nosocomial infections and multiorgan failure. Despite multiple invasive procedures and rescue therapies, he died from the disease. The management of COVID-19 in the posttransplant setting presents complex challenges, emphasizing the importance of strict prevention strategies.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[220] Title: </​b>​Toxic shock-like syndrome and COVID-19: A case report of multisystem inflammatory syndrome in children (MIS-C).<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.25<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-01<​br>​
 +<​b>​Publisher:​ </​b>​American Journal of Emergency Medicine<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-19, child, coronavirus,​ enoxaparin, pediatric, remdesivir, septic, shock, tocilizumab,​ Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0735675720304927">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S0735675720304927</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Early reports of COVID-19 in pediatric populations emphasized a mild course of disease with severe cases disproportionately affecting infant and comorbid pediatric patients. After the peak of the epidemic in New York City, in late April to early May, cases of severe illness associated with COVID-19 were reported among mostly previously healthy children ages 5-19. Many of these cases feature a toxic shock-like syndrome or Kawasaki-like syndrome in the setting of SARS-CoV-2 positive diagnostic testing and the CDC has termed this presentation Multisystem Inflammatory Syndrome (MIS-C). It is essential to disseminate information among the medical community regarding severe and atypical presentations of COVID-19 as prior knowledge can help communities with increasing caseloads prepare to quickly identify and treat these patients as they present in the emergency department. We describe a case of MIS-C in a child who presented to our Emergency Department (ED) twice and on the second visit was found to have signs of distributive shock, multi-organ injury and systemic inflammation associated with COVID-19. The case describes two ED visits by an 11- year-old SARS-CoV-2-positive female who initially presented with fever, rash and pharyngitis and returned within 48 hours with evidence of cardiac and renal dysfunction and fluid-refractory hypotension requiring vasopressors and PICU admission.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[221] Title: </​b>​High-Resolution Computed Tomography Manifestations of 5 Pediatric Patients With 2019 Novel Coronavirus.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11.13<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-01-01<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Computer Assisted Tomography<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​jcat/​FullText/​2020/​05000/​High_Resolution_Computed_Tomography_Manifestations.1.aspx">​https://​journals.lww.com/​jcat/​FullText/​2020/​05000/​High_Resolution_Computed_Tomography_Manifestations.1.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We present clinical and chest computed tomography (CT) features of 5 cases of pediatric patients with 2019 novel coronavirus. Two patients had fever and dry cough, whereas the rest of 3 patients were asymptomatic. Three patients had unilateral ground glass opacities with or without consolidation in the subpleural region on high-resolution chest CT, 1 patient had bilateral ground glass opacities, and 1 patient was negative for CT. We note that up to 66.7% asymptomatic patients had pulmonary lesions, so the asymptomatic children with Wuhan contact are recommended to do a 2019 novel coronavirus real-time fluorescence polymerase chain reaction screening. Unlike adult patients, only a small amount of patients had multilobes affected, so we speculate that the pediatric patients generally have milder CT findings than adults.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[222] Title: </​b>​Guillain-Barre syndrome during SARS-CoV-2 pandemic: A case report and review of recent literature.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​11<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-26<​br>​
 +<​b>​Publisher:​ </​b>​Journal of the Peripheral Nervous System<​br>​
 +<​b>​Keywords:​ </​b>​Neurosciences,​ covid-19, guillain-barre syndrome, sars-cov2, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​jns.12382">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​jns.12382</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Acute demyelinating inflammatory polyneuropathy (AIDP) is the most common type of Guillain-Barre syndrome (GBS) in Europe, following several viral and bacterial infections. Data on AIDP-patients associated with SARS-CoV-2 (coronavirus-2) infection are scarce. We describe the case of a 54-years-old Caucasian female patient with typical clinical and electrophysiological manifestations of AIDP, who was reported positive with PCR for SARS-CoV-2, 3 weeks prior to onset of the neurological symptoms. She did not experience a preceding fever or respiratory symptoms, but a transient loss of smell and taste. At the admission to our neurological department, a progressive proximally pronounced paraparesis,​ areflexia, and sensory loss with tingling of all extremities were found, which began 10 days before. The modified Erasmus Giullain-Barre Syndrome outcome score (mEGOS) was 3/9 at admission and 1/12 at day 7 of hospitalization. The electrophysiological assessment proved a segmental demyelinating polyneuropathy and cerebrospinal fluid examination showed an albuminocytologic dissociation. The neurological symptoms improved significantly during treatment with immunoglobulins. Our case draws attention to the occurrence of GBS also in patients with COVID-19 (coronavirus disease 2019), who did not experience respiratory or general symptoms. It emphasizes that SARS-CoV-2 induces immunological processes, regardless from the lack of prodromic symptoms. However, it is likely that there is a connection between the severity of the respiratory syndrome and further neurological consequences.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[223] Title: </​b>​Pulmonary Pathology of Early Phase COVID-19 Pneumonia in a Patient with a Benign Lung Lesion.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​10.86<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-06<​br>​
 +<​b>​Publisher:​ </​b>​Histopathology<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, 2019 novel coronavirus (sars-cov-2),​ covid-19 pneumonia, t lymphocyte, macrophage, pathology, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​his.14138">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​his.14138</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +AIMS: An ongoing outbreak of 2019 novel coronavirus (SARS-CoV-2) diseases (COVID-19) has been spreading in multiple countries. One of the reasons for the rapid spread is that the virus can be transmitted from infected individuals without symptoms. Revealing the pathological features of early phase COVID-19 pneumonia is important to the understanding of its pathogenesis. The aim of this study was to explore pulmonary pathology of early phase COVID-19 pneumonia in a patient with a benign lung lesion. METHODS AND RESULTS: We analyzed the pathological changes of lung tissue from a 55-year-old female patient with early phase SARS-CoV-2 infection. In this case, right lower lobectomy was performed for a benign pulmonary nodule. Detailed clinical, laboratory and radiological data were also described. This case was confirmed to have preoperative SARS-CoV-2 infection by real-time RT-PCR and RNA in situ hybridization on surgically removed lung tissues. Histologically,​ COVID-19 pneumonia was characterized by exudative inflammation. The closer to the visceral pleura, the more severe the exudation of monocytes and lymphocytes. Perivascular inflammatory infiltration,​ intraalveolar multinucleated giant cells, pneumocyte hyperplasia and intracytoplasmic viral-like inclusion bodies were seen. However, fibrinous exudate and hyaline membrane formation, which were typical pulmonary features of SARS pneumonia, were not evident in this case. Immunohistochemical staining results showed that an abnormal accumulation of CD4+ helper T lymphocytes and CD163+ M2 macrophages in the lung tissue. CONCLUSION: The results highlighted the pulmonary pathological changes of early phase SARS-CoV-2 infection and suggested a role of immune dysfunction in the pathogenesis of COVID-19 pneumonia.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[224] Title: </​b>​Headache as the Presenting Symptom in 2 Patients with COVID-19 and a History of Migraine: 2 Case Reports.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​10.65<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-06-10<​br>​
 +<​b>​Publisher:​ </​b>​Headache:​ The Journal of Head & Face Pain<​br>​
 +<​b>​Keywords:​ </​b>​Clinical Sciences, covid-19, headache, migraine, neurologic, symptoms, Health Sciences, Life Sciences, Medicine, Neuroscience<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​head.13890">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1111/​head.13890</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The Coronavirus disease 2019 (COVID-19) pandemic has now affected more than five million people globally. Typical symptoms include fever, cough, and shortness of breath. Patients with underlying medical comorbidities such as cardiovascular disease and diabetes are more likely to become severely ill. To date there is limited information on how COVID-19 affects patients with a history migraine. Here, we present the cases of 2 women with a history of migraine whose first symptom of COVID-19 was a severe persistent headache.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[225] Title: </b>A Diabetic Patient With 2019-nCoV (COVID-19) Infection Who Recovered and Was Discharged From Hospital.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​10.6<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-05-01<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Thoracic Imaging<​br>​
 +<​b>​Keywords:​ </b>, , Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​journals.lww.com/​thoracicimaging/​FullText/​2020/​05000/​A_Diabetic_Patient_With_2019_nCoV__COVID_19_.16.aspx">​https://​journals.lww.com/​thoracicimaging/​FullText/​2020/​05000/​A_Diabetic_Patient_With_2019_nCoV__COVID_19_.16.aspx</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +Novel coronavirus has become a global health hazard and its high infectivity is alarming. The imaging findings of the 2019-nCoV infection in our young diabetic patient featured ground-glass opacities and consolidations in both lungs. The lung lesions may involute rapidly during the course. The patient showed improvement both clinically and on computed tomography imaging at discharged after 2 weeks' treatment. Computed tomography scans of patients helped monitor the changes continuously,​ which could timely provide the information of the evolution of the disease or therapeutic effect to clinicians.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[226] Title: </b>A Case of Coronavirus Disease 2019 With Concomitant Acute Cerebral Infarction and Deep Vein Thrombosis.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​10.6<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-22<​br>​
 +<​b>​Publisher:​ </​b>​Frontiers in Neurology<​br>​
 +<​b>​Keywords:​ </​b>​Neurosciences,​ covid-19, ct, acute cerebral infarction, case, thrombosis<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​www.frontiersin.org/​articles/​10.3389/​fneur.2020.00296/​full">​https://​www.frontiersin.org/​articles/​10.3389/​fneur.2020.00296/​full</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +We report a case of a 75-year-old woman diagnosed with severe coronavirus disease 2019 (COVID-19) complicated by acute cerebral infarction. The patient was admitted to our hospital on 5 February 2020 with severe COVID-19. On 20 February 2020, she was diagnosed with concomitant acute cerebral infarction via head computed tomography (CT) and deep vein thrombosis in both lower limbs. After symptomatic and supportive treatments, the patient was discharged on 13 March 2020. She will comply with quarantine for another 2 weeks and receive rehabilitation training from a specialist doctor. Cerebral infarction should be considered and promptly managed in patients with COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[227] Title: </​b>​SARS-CoV-2 turned positive in a discharged patient with COVID-19 arouses concern regarding the present standard for discharge.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​10.2<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-03-01<​br>​
 +<​b>​Publisher:​ </​b>​International Journal of Infectious Diseases<​br>​
 +<​b>​Keywords:​ </​b>​Microbiology,​ covid-19, discharge standard, turn positive, Medicine, Health Sciences<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1201971220301260">​https://​linkinghub.elsevier.com/​retrieve/​pii/​S1201971220301260</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +An outbreak of COVID-19 in Wuhan, China caused by SARS-CoV-2 has led to a serious epidemic in China and other countries, resulting in worldwide concern. With the active efforts from prevention and control, the quantity of discharged patients is escalating. How to manage these patients normatively is still challenging. We hereby reported an asymptomatic discharged patient with COVID-19 who was retested positive for SARS-CoV-2, which arouses concern regarding the present discharge standard of COVID-19.<​br>​
 +----------------------------------------------------------------------<​br><​br>​
 +----------------------------------------------------------------------<​br>​
 +<​b>​[228] Title: </​b>​Off-label Use of Tocilizumab in Patients with SARS-CoV-2 Infection.<​br><​br>​
 +<​b>​Altmetric Score: </​b>​10.05<​br>​
 +<​b>​Pub_Date:​ </​b>​2020-04-16<​br>​
 +<​b>​Publisher:​ </​b>​Journal of Medical Virology<​br>​
 +<​b>​Keywords:​ </​b>​Medical Microbiology,​ covid-19, sars-cov-2, interstitial pneumonia, tocilizumab,​ Health Sciences, Life Sciences, Medicine, Immunology and Microbiology<​br>​
 +<​b>​DOI:​ </​b><​a href="​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​jmv.25897">​https://​onlinelibrary.wiley.com/​doi/​abs/​10.1002/​jmv.25897</​a><​br><​br>​
 +<​b>​Abstract:​ </b>
 +The spread of the novel-Coronavirus infection worldwide represents a challenge for physicians. Particularly,​ no approved therapy has demonstrated to have an impact in treating patients who develop severe respiratory insufficiency so far. The use of humanized anti-human inteleukine-6 receptor antibody tocilizumab seems a promising strategy for these patients. This article is protected by copyright. All rights reserved.<​br>​
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 +
 +
 +</​html>​
oa_db/covid19_case_reports_abstracts_pg4.txt · Last modified: 2020/06/28 04:03 by bpwhite